SCHEMBL31270

SCHEMBL31270

COCc1ccc(OC)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.67
AGXT P21549 2/20 0.67
CA12 O43570 1/20 0.58
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
CA7 P43166 1/20 0.58
CA9 Q16790 1/20 0.58
CA14 Q9ULX7 1/20 0.58
APP P05067 5/20 0.57
MAOB P27338 1/20 0.55
LTA4H P09960 1/20 0.54
TAAR1 Q96RJ0 1/20 0.54
CALM1 P0DP23 1/20 0.54
SMN1; SMN2 Q16637 2/20 0.52
ALDH1A1 P00352 1/20 0.52
TP53 P04637 1/20 0.52
CYP3A4 P08684 1/20 0.52
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.52
ALOX12 P18054 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12736296 0.93 IDO1 (0.59) IDO1AGXTCA12CA1CA2
SCHEMBL18437081 0.93 IDO1 (0.59) IDO1AGXTCA12CA1CA2
SCHEMBL11591739 0.87 IDO1 (0.53) IDO1AGXTCA12CA1CA2
SCHEMBL134443 0.86 IDO1 (0.46) IDO1AGXTAPPMAOBTP53
SCHEMBL34413 0.84 IDO1 (0.67) IDO1AGXTCA12CA1CA2
SCHEMBL6327626 0.84 IDO1 (0.48) IDO1AGXTAPPMAOBLTA4H
SCHEMBL4534313 0.84 CYP1A2 (0.58) IDO1AGXTCA1CA2APP
SCHEMBL13126264 0.82 MAOB (0.49) IDO1AGXTAPPMAOBCALM1
SCHEMBL19684429 0.82 TDP1 (0.50) IDO1AGXTCA1CA2MAOB
Potassium SCHEMBL1477050 0.82 IDO1 (0.64) IDO1AGXTCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4408 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504386-A Method for preparing anisic aldehyde 河南农业大学 2025-02-25 CN claimed
WO-2024093947-A1 PRODRUG FOR DELIVERING SIRNA INTO CELL 大睿生物医药科技(上海)有限公司 2024-05-10 WO claimed
WO-2024093907-A1 LIGAND FOR DELIVERING SIRNA TO EYE AND CENTRAL NERVOUS SYSTEM 大睿生物医药科技(上海)有限公司 2024-05-10 WO claimed
CN-117897440-A Method for screening solvent for extraction of polyvinyl chloride, method for recycling waste material, recycled polyvinyl chloride and composition 株式会社LG化学 2024-04-16 CN claimed
CN-117897439-A Method for screening solvent for extraction of polyvinyl chloride, method for recovering waste material, and recovered polyvinyl chloride and composition 株式会社LG化学 2024-04-16 CN claimed
EP-2991655-B1 COMPOSITIONS AND METHODS FOR ALTERING SECOND MESSENGER SIGNALING MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2024-04-10 EP claimed
CN-117659032-A Intermediate of ecteinascidin derivative and synthetic method thereof 南通诺泰生物医药技术有限公司 2024-03-08 CN claimed
US-20230374060-A1 NOVEL METHOD FOR PREPARING INOTODIOL DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) 2023-11-23 US claimed
EP-3606528-B1 TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF BROAD INST INC (US) 2023-10-18 EP claimed
CN-110997645-B Preparation method of ozagrel 埃吉斯制药公司 2023-10-10 CN claimed
US-5583235-A ALKENYLATION, CYCLIZATION SHAMAN PHARMACEUTICALS, INC. (US) 1996-12-10 US claimed
EP-0711773-A1 HYMENIALDISINE AND DERIVATIVE THEREOF, PROCESS FOR PRODUCING INTERMEDIATE FOR SYNTHESIZING THE SAME, AND SAID INTERMEDIATE SUNTORY LIMITED (JP) 1996-05-15 EP claimed
WO-1996003388-A1 1,2-SUBSTITUTED IMIDAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1996-02-08 WO claimed
WO-1995029923-A1 PROCESS FOR THE PREPARATION OF MONO- AND BIS(PHOSPHOCHOLINE) DERIVATIVES WHICH HAVE ANTIFUNGAL ACTIVITY SHAMAN PHARMACEUTICALS, INC. (US) 1995-11-09 WO claimed
EP-0292808-B1 Substituted vinyl cephalosporins, process for their preparation and their use as medicines BAYER AG (DE) 1994-03-02 EP claimed
US-5278332-A Derivatives of cyclohexane PERSTORP AB (SE) 1994-01-11 US claimed
US-4880624-A GUAIACOL, TRIMETHOXYBENZENE THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1989-11-14 US claimed
US-4849531-A Process for the preparation of 2,3-epoxyamides BAYER AKTIENGESELLSCHAFT (DE) 1989-07-18 US claimed
EP-0292808-A2 Substituted vinyl cephalosporins, process for their preparation and their use as medicines BAYER AG (DE) 1988-11-30 EP claimed
EP-0244717-A2 Process for the preparation of 2,3-epoxyamides BAYER AG (DE) 1987-11-11 EP claimed