SCHEMBL1131322

SCHEMBL1131322

F[Zr](F)(c1cccc2c1Cc1ccccc1-2)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.49
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
HTR7 P34969 2/20 0.40
HTR2B P41595 2/20 0.40
MAOA P21397 1/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
SRD5A2 P31213 1/20 0.36
DRD2 P14416 2/20 0.35
DRD4 P21917 1/20 0.35
DRD3 P35462 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3384059 0.89 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL30536713 0.81 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL7602119 0.81 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL3385667 0.81 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL3384917 0.81 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL618217 0.81 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL7878851 0.81 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL3385391 0.81 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL8755327 0.79 PNMT (0.47) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL30103334 0.79 PNMT (0.63) PNMTNPC1RAB9AHTR7HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1673401-B1 POLYMERIZATION PROCESS AND CONTROL OF POLYMER COMPOSITION PROPERTIES UNIVATION TECH LLC (US) 2015-10-21 EP disclosed
EP-1546212-B1 BIMODAL POLYOLEFIN PRODUCTION PROCESS AND FILMS THEREFROM UNIVATION TECH LLC (US) 2011-02-16 EP disclosed
EP-1673400-A4 POLYMERIZATION PROCESS AND CONTROL OF POLYMER COMPOSITION PROPERTIES UNIVATION TECH LLC (US) 2007-07-11 EP disclosed
EP-1673401-A4 POLYMERIZATION PROCESS AND CONTROL OF POLYMER COMPOSITION PROPERTIES UNIVATION TECH LLC (US) 2007-07-11 EP disclosed
US-7238756-B2 Polymerization process and control of polymer composition properties UNIVATION TECHNOLOGIES, LLC (US) 2007-07-03 US disclosed
EP-1551553-A4 PROCESS FOR PRODUCING FLUORINATED CATALYSTS UNIVATION TECH LLC (US) 2007-05-09 EP disclosed
EP-1546212-A4 BIMODAL POLYOLEFIN PRODUCTION PROCESS AND FILMS THEREFROM UNIVATION TECH LLC (US) 2006-07-05 EP disclosed
EP-1673401-A1 POLYMERIZATION PROCESS AND CONTROL OF POLYMER COMPOSITION PROPERTIES Univation Technologies, LLC (US) 2006-06-28 EP disclosed
EP-1673400-A1 POLYMERIZATION PROCESS AND CONTROL OF POLYMER COMPOSITION PROPERTIES Univation Technologies, LLC (US) 2006-06-28 EP disclosed
EP-1560857-A4 SYNTHESIS OF POLYMERIZATION CATALYST COMPONENTS UNIVATION TECH LLC (US) 2006-04-19 EP disclosed
US-20050038210-A1 Bimodal polyolefin production process and films therefrom KUO CHI-I (US) 2005-02-17 US disclosed
US-6855784-B2 Synthesis of polymerization catalyst components UNIVATION TECHNOLOGIES, LLC (US) 2005-02-15 US disclosed
US-6828395-B1 Polymerization process and control of polymer composition properties UNIVATION TECHNOLOGIES, LLC 2004-12-07 US disclosed
US-20040236045-A1 SYNTHESIS OF POLYMERIZATION CATALYST COMPONENTS MATSUNAGA PHILLIP T (US) 2004-11-25 US disclosed
WO-2004044010-A2 SYNTHESIS OF POLYMERIZATION CATALYST COMPONENTS UNIVATION TECHNOLOGIES, LLC (US) 2004-05-27 WO disclosed
US-20040092387-A1 Synthesis of polymerization catalyst components UNIVATION TECHNOLOGIES, LLC 2004-05-13 US disclosed
WO-2004022230-A1 PROCESS FOR PRODUCING FLUORINATED CATALYSTS UNIVATION TECHNOLOGIES, LLC (US) 2004-03-18 WO disclosed
WO-2004022607-A1 BIMODAL POLYOLEFIN PRODUCTION PROCESS AND FILMS THEREFROM UNIVATION TECHNOLOGIES, LLC (US) 2004-03-18 WO disclosed
US-20040044154-A1 Bimodal polyolefin production process and films therefrom UNIVATION TECHNOLOGIES, LLC 2004-03-04 US disclosed
US-20040043893-A1 Process for producing fluorinated catalysts UNIVATION TECHNOLOGIES, LLC 2004-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040043893-A1 Process for producing fluorinated catalysts FLI1, AFF1, INF2 PNMT 463/4885NPC1 2245/4885RAB9A 711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.