Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.57 |
| ▸ | TTR | P02766 | 4/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11324534 | 0.89 | MCL1 (0.57) | MCL1TTRMEN1KMT2AKDM4E | |
| SCHEMBL11311546 | 0.83 | MAPT (0.49) | MCL1MEN1KMT2AKDM4ECA12 | |
| SCHEMBL11314882 | 0.81 | ACP1 (0.46) | TTRMEN1KMT2AKDM4ECA12 | |
| SCHEMBL11324807 | 0.81 | MCL1 (0.39) | MCL1MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL11325086 | 0.80 | KDM4E (0.61) | CA1CA2MEN1KMT2AKDM4E | |
| SCHEMBL11323420 | 0.80 | KMO (0.40) | MCL1TTRKDM4ECA12CA9 | |
| SCHEMBL11179425 | 0.80 | MCL1 (0.51) | MCL1TTRCA1CA2MEN1 | |
| SCHEMBL6329907 | 0.78 | MCL1 (0.80) | MCL1TTRCA1CA2MEN1 | |
| SCHEMBL11323531 | 0.76 | KDM4E (0.50) | MCL1TTRCA1CA2KMT2A | |
| SCHEMBL11321162 | 0.75 | CSNK2A2 (0.50) | MCL1TTRKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4307020-A | REACTING AN 0-HYDROXYACETOPHENONE WITH A GLYOXYLIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 1981-12-22 | — | — | US | disclosed |
| US-4285965-A | FUNGICIDES AND INSECTICIDES FOR PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-25 | — | — | US | disclosed |
| EP-0000377-B1 | PROCESS FOR THE PREPARATION OF CHROMONE DERIVATIVES, NEW CHROMONE DERIVATIVES AND THEIR USE AS PLANT-PROTECTING AGENTS | BAYER AG (DE) | 1981-01-21 | — | — | EP | disclosed |
| US-4189498-A | FUNGICIDES, ARTHROPODICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-19 | — | — | US | disclosed |