SCHEMBL1131345

SCHEMBL1131345

CC(=O)C1(CC(C)C)C=CC=CC1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.35
CYP3A4 P08684 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetonitrile SCHEMBL28747282 0.92 MAPK1 (0.31) MAPK1
SCHEMBL5614141 0.79
SCHEMBL11582266 0.78
Acetonitrile SCHEMBL27539961 0.77
SCHEMBL28244218 0.76
Acetonitrile SCHEMBL28745506 0.72
SCHEMBL28653583 0.70 KMT2A (0.37)
SCHEMBL6667419 0.70 HSD11B1 (0.37) CYP3A4
SCHEMBL27651280 0.69
SCHEMBL9551675 0.69 MAPK1 (0.31) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1670738-B1 CATALYSED ACYLATION OF ALKYLATED BENZENE DERIVATIVES COUNCIL SCIENT IND RES (IN) 2011-02-16 EP claimed
EP-0488638-B1 BF3 catalyzed acetylation of butylbenzene HOECHST CELANESE CORP (US) 1997-01-02 EP claimed
JP-2117631-A None JP disclosed
JP-H02117631-A PRODUCTION OF 1-(4'-ISOBUTYLPHENYL)ETHANOL HOECHST CELANESE CORP 1990-05-02 JP disclosed