Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.64 |
| ▸ | RAB9A | P51151 | 6/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 1/20 | 0.57 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | JAK1 | P23458 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11313281 | 0.87 | NPC1 (0.60) | NPC1RAB9APDE4DL3MBTL1ALDH1A1 | |
| SCHEMBL11322971 | 0.87 | NPC1 (0.66) | NPC1RAB9AL3MBTL1ALDH1A1CNR2 | |
| SCHEMBL30523322 | 0.87 | MAPT (0.52) | NPC1RAB9APDE4DCNR2NPSR1 | |
| SCHEMBL29071271 | 0.87 | MAPT (0.52) | NPC1RAB9APDE4DCNR2NPSR1 | |
| SCHEMBL11314665 | 0.84 | NPC1 (0.57) | NPC1RAB9AALDH1A1NPSR1MAPT | |
| SCHEMBL11174674 | 0.84 | JAK2 (0.57) | ALDH1A1JAK2JAK1LMNAMAPT | |
| SCHEMBL23602954 | 0.84 | NPC1 (0.66) | NPC1RAB9APDE4DL3MBTL1ALDH1A1 | |
| SCHEMBL14566867 | 0.84 | JAK2 (0.55) | NPC1PDE4DJAK2JAK1LMNA | |
| SCHEMBL11313791 | 0.83 | LMNA (0.64) | NPC1RAB9AALDH1A1CNR2NPSR1 | |
| SCHEMBL3319357 | 0.82 | PDE4D (0.78) | NPC1RAB9APDE4DL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4263205-A | FOR COLORING POLYMERS, LACQUERS | CIBA-GEIGY CORPORATION (US) | 1981-04-21 | — | — | US | disclosed |
| US-4031073-A | Monoazo pigments containing barbituric acid or thio- or imino-derivatives thereof | CIBA-GEIGY CORPORATION (US) | 1977-06-21 | — | — | US | disclosed |