Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7063128 | 0.80 | LMNA (0.42) | LMNACA12CA1CA2CA3 | |
| Butane SCHEMBL11313859 | 0.80 | LMNA (0.44) | LMNACA12CA1CA2CA3 | |
| SCHEMBL7062761 | 0.78 | LMNA (0.40) | LMNACA12CA1CA2CA3 | |
| SCHEMBL951298 | 0.75 | LMNA (0.51) | LMNACA12CA1CA2CA3 | |
| SCHEMBL10959845 | 0.75 | LMNA (0.51) | LMNACA12CA1CA2CA3 | |
| SCHEMBL11309197 | 0.72 | MAPK1 (0.42) | HTTPSMD14L3MBTL1MAPK1KMT2A | |
| SCHEMBL3728882 | 0.71 | LMNA (0.46) | LMNACA12CA1CA2CA3 | |
| SCHEMBL7062342 | 0.71 | LMNA (0.40) | LMNACA12CA1CA2CA3 | |
| SCHEMBL7514608 | 0.71 | PIM1 (0.38) | LMNACA12CA1CA2CA3 | |
| SCHEMBL11187859 | 0.70 | LMNA (0.45) | LMNACA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4341790-A | CEREBRAL CIRCULATORY, ATROPHY, AND AGING | A. NATTERMANN & CIE. GMBH (DE) | 1982-07-27 | — | — | US | disclosed |