Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.81 |
| ▸ | CASP2 | P42575 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.69 |
| ▸ | FAAH | O00519 | 1/20 | 0.68 |
| ▸ | NAAA | Q02083 | 1/20 | 0.67 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.65 |
| ▸ | PPARG | P37231 | 6/20 | 0.65 |
| ▸ | PPARD | Q03181 | 6/20 | 0.65 |
| ▸ | PPARA | Q07869 | 6/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.65 |
| ▸ | TSHR | P16473 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | TLR2 | O60603 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | FABP4 | P15090 | 2/20 | 0.65 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.65 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.65 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15649579 | 1.00 | EPHX2 (0.81) | EPHX2CASP2KDM4EPLA2G2AFAAH | |
| SCHEMBL9266547 | 1.00 | EPHX2 (0.81) | EPHX2CASP2KDM4EPLA2G2AFAAH | |
| SCHEMBL8044633 | 1.00 | EPHX2 (0.81) | EPHX2CASP2KDM4EPLA2G2AFAAH | |
| SCHEMBL15259281 | 1.00 | EPHX2 (0.81) | EPHX2CASP2KDM4EPLA2G2AFAAH | |
| SCHEMBL8041499 | 1.00 | EPHX2 (0.81) | EPHX2CASP2KDM4EPLA2G2AFAAH | |
| SCHEMBL23052005 | 1.00 | EPHX2 (0.81) | EPHX2CASP2KDM4EPLA2G2AFAAH | |
| SCHEMBL16013677 | 1.00 | EPHX2 (0.81) | EPHX2CASP2KDM4EPLA2G2AFAAH | |
| SCHEMBL22072061 | 1.00 | EPHX2 (0.81) | EPHX2CASP2KDM4EPLA2G2AFAAH | |
| SCHEMBL22684645 | 1.00 | EPHX2 (0.81) | EPHX2CASP2KDM4EPLA2G2AFAAH | |
| SCHEMBL2150959 | 1.00 | EPHX2 (0.81) | EPHX2CASP2KDM4EPLA2G2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859756-B1 | PREPARATION OF AMIDO ESTER COMPOUNDS | EASTMAN CHEM CO (US) | 2000-04-05 | — | — | EP | claimed |
| EP-0859756-A1 | PREPARATION OF AMIDO ESTER COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 1998-08-26 | — | — | EP | claimed |
| US-5650527-A | CONTROLLED ADDITION OF ANHYDRIDE TO REACTION MIXTURE OF AMIDO-CARBOXYLIC ACID AND PHENOL WITH ELECTRON WITHDRAWING GROUPS, ESTER INTERCHANGE CATALYST | EASTMAN CHEMICAL COMPANY (US) | 1997-07-22 | — | — | US | claimed |
| WO-1996039378-A1 | PREPARATION OF AMIDO ESTER COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 1996-12-12 | — | — | WO | claimed |
| US-20260062580-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT | THE PILOT INK CO., LTD. (JP) | 2026-03-05 | — | — | US | disclosed |
| US-12460099-B2 | Reversibly thermochromic composition, reversibly thermochromic microcapsule pigment encapsulating reversibly thermochromic composition, and writing instrument using reversibly thermochromic microcapsule pigment | THE PILOT INK CO., LTD. (JP) | 2025-11-04 | — | — | US | disclosed |
| EP-3608386-B1 | REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN | PILOT INK CO LTD (JP) | 2025-02-19 | — | — | EP | disclosed |
| US-12123107-B2 | Reversibly thermochromic composite fiber | KABUSHIKI KAISHA PILOT CORPORATION (JP) | 2024-10-22 | — | — | US | disclosed |
| CN-113646052-B | Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument | 百乐墨水株式会社 | 2024-05-17 | — | — | CN | disclosed |
| US-20220169919-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT | THE PILOT INK CO., LTD. (JP) | 2022-06-02 | — | — | US | disclosed |
| EP-3950068-A1 | REVERSIBLE THERMOCHROMIC COMPOSITION, REVERSIBLE THERMOCHROMIC MICROCAPSULE PIGMENT COMPRISING SAME, AND WRITING INSTRUMENT USING SAME | THE PILOT INK CO., LTD. (JP) | 2022-02-09 | — | — | EP | disclosed |
| US-20210355608-A1 | REVERSIBLY THERMOCHROMIC COMPOSITE FIBER | THE PILOT INK CO., LTD. (JP) | 2021-11-18 | — | — | US | disclosed |
| WO-2004067689-A1 | DETERGENT COMPOSITIONS | UNILEVER PLC (GB) | 2004-08-12 | — | — | WO | disclosed |
| EP-0873881-B1 | Reversible thermochromic compositions | PILOT INK CO LTD (JP) | 2001-10-17 | — | — | EP | disclosed |
| EP-0859756-B1 | PREPARATION OF AMIDO ESTER COMPOUNDS | EASTMAN CHEM CO (US) | 2000-04-05 | — | — | EP | disclosed |
| US-5919404-A | MIXTURE OF COLOR DEVELOPING COMPOUND AND ELECTRON ACCEPTORALKOXYPHENOL COMPOUND | THE PILOT INK CO., LTD. (JP) | 1999-07-06 | — | — | US | disclosed |
| EP-0873881-A1 | Reversible thermochromic compositions | The Pilot Ink CO., Ltd. (JP) | 1998-10-28 | — | — | EP | disclosed |
| EP-0859756-A1 | PREPARATION OF AMIDO ESTER COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 1998-08-26 | — | — | EP | disclosed |
| US-5650527-A | CONTROLLED ADDITION OF ANHYDRIDE TO REACTION MIXTURE OF AMIDO-CARBOXYLIC ACID AND PHENOL WITH ELECTRON WITHDRAWING GROUPS, ESTER INTERCHANGE CATALYST | EASTMAN CHEMICAL COMPANY (US) | 1997-07-22 | — | — | US | disclosed |
| WO-1996039378-A1 | PREPARATION OF AMIDO ESTER COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 1996-12-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260062580-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT | TYR, SCO2, HBB | EPHX2 2279/4885CASP2 1862/4885KDM4E 3963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.