Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL676001 | 0.84 | KDM4E (0.50) | CYP1A2CYP2D6CYP2C9CYP2C19CYP19A1 | |
| SCHEMBL38650638 | 0.84 | KDM4E (0.50) | CYP1A2CYP2D6CYP2C9CYP2C19CYP19A1 | |
| Hydrochloric Acid SCHEMBL7056332 | 0.83 | CYP1A2 (0.49) | CYP1A2CYP2D6CYP2C9CYP2C19CYP19A1 | |
| SCHEMBL5570130 | 0.83 | CYP1A2 (0.49) | CYP1A2CYP2D6CYP2C9CYP2C19CYP19A1 | |
| SCHEMBL28850621 | 0.77 | MEN1 (0.48) | CYP1A2CYP2D6CYP2C9CYP2C19CYP19A1 | |
| SCHEMBL9848049 | 0.74 | KDM4E (0.60) | CYP1A2CYP2D6CYP2C9CYP2C19CYP19A1 | |
| SCHEMBL27521956 | 0.72 | TDP1 (0.48) | CYP1A2CYP2D6CYP2C9CYP2C19CYP19A1 | |
| SCHEMBL7052857 | 0.70 | TSHR (0.44) | CYP1A2CYP2D6CYP2C9KDM4ELMNA | |
| Oxazole SCHEMBL27635121 | 0.70 | KDM4E (0.58) | CYP1A2CYP19A1KDM4ELMNAPOLB | |
| SCHEMBL4812728 | 0.70 | CCR1 (0.50) | CYP1A2CYP19A1KDM4ELMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0006176-B1 | STILBENE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-01-06 | — | — | EP | disclosed |
| EP-0006176-A1 | Stilbene compounds, process for their preparation and their use as optical brighteners | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-01-09 | — | — | EP | disclosed |