Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | CCR1 | P32246 | 3/20 | 0.60 |
| ▸ | CCR5 | P51681 | 3/20 | 0.60 |
| ▸ | CCR8 | P51685 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | ALPL | P05186 | 1/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
| ▸ | ALPI | P09923 | 1/20 | 0.60 |
| ▸ | ALPG | P10696 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL676001 | 0.88 | KDM4E (0.50) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL38650638 | 0.88 | KDM4E (0.50) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL15048694 | 0.86 | KDM4E (0.51) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL5570130 | 0.86 | CYP1A2 (0.49) | KDM4ECCR1CCR5CCR8LMNA | |
| Hydrochloric Acid SCHEMBL7056332 | 0.86 | CYP1A2 (0.49) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL10533031 | 0.86 | RAB9A (0.52) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL13202960 | 0.86 | KDM4E (0.82) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL4812728 | 0.85 | CCR1 (0.50) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL20207976 | 0.81 | KDM4E (0.67) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL28850621 | 0.80 | MEN1 (0.48) | KDM4ECCR1CCR5CCR8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451585-A2 | 2-aryl-6-hetarylpyridine derivatives | BAYER AG (DE) | 1991-10-16 | — | — | EP | claimed |
| EP-0451585-A2 | 2-aryl-6-hetarylpyridine derivatives | BAYER AG (DE) | 1991-10-16 | — | — | EP | disclosed |