Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3666306 | 0.95 | TSHR (0.53) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL15495137 | 0.91 | TSHR (0.70) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL22829484 | 0.91 | TSHR (0.70) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL13398343 | 0.87 | TSHR (0.63) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL32689960 | 0.86 | TSHR (0.59) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL19881815 | 0.85 | TSHR (0.61) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL28986661 | 0.85 | TSHR (0.61) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL11329528 | 0.85 | TSHR (0.61) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL20193649 | 0.83 | TSHR (0.68) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL21443918 | 0.83 | TSHR (0.58) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4293600-A | SAID ACRYLIC RESINS BEING CROSSLINKED AND OF THE ESTER OR AMIDE TYPE | ROHM GMBH (DE) | 1981-10-06 | — | — | US | disclosed |
| US-4239671-A | FINISHES FOR TEXTILES | ROHM GMBH (DE) | 1980-12-16 | — | — | US | disclosed |