Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.38 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1131560 | 1.00 | ALOX5 (0.43) | ALOX5SMN1; SMN2KDM4EKMT2AGSK3B | |
| SCHEMBL1131706 | 0.91 | ALOX5 (0.42) | ALOX5SMN1; SMN2KDM4EKMT2AGSK3B | |
| SCHEMBL1131710 | 0.91 | ALOX5 (0.42) | ALOX5SMN1; SMN2KDM4EKMT2AGSK3B | |
| SCHEMBL1131252 | 0.91 | PRMT5 (0.41) | ALOX5SMN1; SMN2KDM4EKMT2ABTK | |
| SCHEMBL1131256 | 0.91 | PRMT5 (0.41) | ALOX5SMN1; SMN2KDM4EKMT2ABTK | |
| SCHEMBL12860107 | 0.86 | S1PR1 (0.38) | SMN1; SMN2KDM4EKMT2ARAB9AALDH1A1 | |
| SCHEMBL12860137 | 0.85 | CA12 (0.42) | ALOX5KDM4EKMT2AALDH1A1HPGD | |
| SCHEMBL1131481 | 0.84 | PTPN1 (0.44) | ALOX5SMN1; SMN2KDM4EKMT2ABTK | |
| SCHEMBL1131573 | 0.84 | PTPN1 (0.44) | ALOX5SMN1; SMN2KDM4EKMT2ABTK | |
| SCHEMBL1131258 | 0.81 | ALOX5 (0.41) | ALOX5SMN1; SMN2KDM4EKMT2ABTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663105-B1 | CYCLOALKYL HETEROCYCLES FOR TREATING HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2011-02-16 | — | — | EP | claimed |
| EP-1663105-B1 | CYCLOALKYL HETEROCYCLES FOR TREATING HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2011-02-16 | — | — | EP | disclosed |