Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 5/20 | 0.48 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202415 | 0.76 | KCNN4 (0.39) | KCNN4ALDH1A1MAPK1HDAC3HDAC4 | |
| SCHEMBL3246877 | 0.76 | TSHR (0.44) | KCNN4KIF11TSHRALDH1A1MIF | |
| SCHEMBL3247516 | 0.76 | TSHR (0.44) | KCNN4TSHRALDH1A1MIFMAPK1 | |
| SCHEMBL2074396 | 0.75 | KCNN4 (0.48) | KCNN4KIF11TSHRALDH1A1MAPK1 | |
| SCHEMBL10879895 | 0.75 | KCNN4 (0.48) | KCNN4KIF11TSHRALDH1A1MAPK1 | |
| SCHEMBL3246631 | 0.72 | CYP2D6 (0.36) | KCNN4TSHRALDH1A1MIFMAPK1 | |
| SCHEMBL2363005 | 0.69 | KCNN4 (0.60) | KCNN4KIF11TSHRALDH1A1MAPK1 | |
| SCHEMBL21839329 | 0.69 | KCNN4 (0.60) | KCNN4KIF11TSHRALDH1A1MAPK1 | |
| Ammonia Solution, Strong SCHEMBL28866362 | 0.67 | KCNN4 (0.57) | KCNN4KIF11TSHRALDH1A1MAPK1 | |
| Hydrogen Sulfide SCHEMBL28100574 | 0.67 | KCNN4 (0.57) | KCNN4KIF11TSHRALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4246405-A | Method for preparation of β-lactam compound | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1981-01-20 | — | — | US | claimed |
| US-4246405-A | Method for preparation of β-lactam compound | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1981-01-20 | — | — | US | disclosed |