SCHEMBL2363005

SCHEMBL2363005

c1ccc(C(NC(c2ccccc2)(c2ccccc2)c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 5/20 0.60
KIF11 P52732 1/20 0.48
ALDH1A1 P00352 3/20 0.45
TSHR P16473 2/20 0.45
MAPK1 P28482 1/20 0.39
CYP1A2 P05177 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
ALOX15 P16050 1/20 0.36
HDAC3 O15379 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC10 Q969S8 1/20 0.36
HDAC11 Q96DB2 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
HDAC9 Q9UKV0 1/20 0.36
HDAC5 Q9UQL6 1/20 0.36
CTSD P07339 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28866362 0.97 KCNN4 (0.57) KCNN4KIF11ALDH1A1TSHRMAPK1
SCHEMBL18035828 0.83 KCNN4 (0.56) KCNN4KIF11ALDH1A1TSHRMAPK1
Pyrrolidine SCHEMBL28823413 0.81 KCNN4 (0.43) KCNN4KIF11ALDH1A1MAPK1CYP1A2
SCHEMBL21839329 0.80 KCNN4 (0.60) KCNN4KIF11ALDH1A1TSHRMAPK1
Piperidine SCHEMBL28823404 0.79 KCNN4 (0.41) KCNN4KIF11ALDH1A1MAPK1CYP1A2
SCHEMBL3232887 0.75 KCNN4 (0.55) KCNN4KIF11ALDH1A1TSHRMAPK1
SCHEMBL9867906 0.75 KCNN4 (0.55) KCNN4KIF11ALDH1A1TSHRMAPK1
SCHEMBL11767238 0.75 KCNN4 (0.55) KCNN4KIF11ALDH1A1TSHRMAPK1
SCHEMBL3228004 0.75 KCNN4 (0.55) KCNN4KIF11ALDH1A1TSHRMAPK1
SCHEMBL316124 0.75 KCNN4 (0.55) KCNN4KIF11ALDH1A1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230355530-A1 PARTICLES COMPRISING A THERAPEUTIC OR DIAGNOSTIC AGENT AND SUSPENSIONS AND METHODS OF USE THEREOF HALOZYME HYPERCON, INC. 2023-11-09 US claimed
US-20230094393-A1 PEPTIDE PARTICLES AND METHODS OF FORMATION ELEKTROFI, INC. 2023-03-30 US claimed
EP-4027978-A1 COMPOSITIONS AND METHODS FOR THE DELIVERY OF THERAPEUTIC BIOLOGICS FOR TREATMENT OF DISEASE Elektrofi, Inc. (US) 2022-07-20 EP claimed
EP-3917500-A2 PARTICLE FORMATION AND MORPHOLOGY Elektrofi, Inc. (US) 2021-12-08 EP claimed
WO-2021158959-A2 PEPTIDE PARTICLES AND METHODS OF FORMATION ELEKTROFI, INC. (US) 2021-08-12 WO claimed
US-20210220289-A1 PARTICLES COMPRISING A THERAPEUTIC OR DIAGNOSTIC AGENT AND SUSPENSIONS AND METHODS OF USE THEREOF HALOZYME HYPERCON, INC. 2021-07-22 US claimed
WO-2021050953-A1 COMPOSITIONS AND METHODS FOR THE DELIVERY OF THERAPEUTIC BIOLOGICS FOR TREATMENT OF DISEASE ELEKTROFI, INC. (US) 2021-03-18 WO claimed
WO-2020160323-A2 PARTICLE FORMATION AND MORPHOLOGY ELEKTROFI, INC. (US) 2020-08-06 WO claimed
EP-3544724-A1 PARTICLES COMPRISING A THERAPEUTIC OR DIAGNOSTIC AGENT AND SUSPENSIONS AND METHODS OF USE THEREOF Elektrofi, Inc (US) 2019-10-02 EP claimed
CN-107001892-B Adhesive comprising multi-functional siloxanes water scavenger 德莎欧洲股份公司 2019-09-06 CN claimed
CN-108140881-A Improved electrolyte, current collector and binder for rechargeable metal ion batteries 里兰斯坦福初级大学理事会 2018-06-08 CN claimed
EP-1362572-B2 Use of at least one particular organic salt for cleansing and/or conditioning keratinous materials, use of a particular organic salt as conditioning agent for said materials and process for cosmetic treatment OREAL (FR) 2011-08-17 EP claimed
WO-2010125302-A1 USE OF IONIC LIQUID FOR THE PERMANENT SHAPING OF KERATINIC FIBRES L'OREAL (FR) 2010-11-04 WO claimed
EP-1362572-B1 Use of at least one particular organic salt for cleansing and/or conditioning keratinous materials, use of a particular organic salt as conditioning agent for said materials and process for cosmetic treatment OREAL (FR) 2008-04-16 EP claimed
EP-1649894-A2 Composition comprising electrophilic monomers and organic salts, use for treatment of keratinic materials L'OREAL (FR) 2006-04-26 EP claimed
US-20050065020-A1 Ionic liquids containing secondary hydroxyl-groups and a method for their preparation UNIVERSITY OF ALABAMA (US) 2005-03-24 US claimed
EP-1362572-A1 Cosmetic composition comprising at least one particular organic salt and its use for cleansing and/or conditioning keratinous materials, use of a particular organic salt as conditioning agent for said materials and process for cosmetic treatment L'OREAL (FR) 2003-11-19 EP claimed
US-6631761-B2 Wet electric heating process ALBERTA SCIENCE AND RESEARCH AUTHORITY (CA) 2003-10-14 US claimed
US-20030141053-A1 Wet electric heating process INNOTECH ALBERTA INC. (CA) 2003-07-31 US claimed
WO-2003054351-A1 WET ELECTRIC HEATING PROCESS ALBERTA SCIENCE AND RESEARCH AUTHORITY (CA) 2003-07-03 WO claimed