Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 9/20 | 0.44 |
| ▸ | ACE | P12821 | 4/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11315822 | 0.84 | CMA1 (0.52) | — | |
| SCHEMBL10829164 | 0.81 | ACE (0.44) | KLK7KLK5ACEDPP4DPP8 | |
| SCHEMBL8366819 | 0.81 | DPP4 (0.58) | KLK5ACEDPP4DPP8DPP9 | |
| SCHEMBL7321073 | 0.81 | DPP4 (0.58) | KLK5ACEDPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL7296993 | 0.80 | DPP4 (0.57) | KLK5ACEDPP4DPP8DPP9 | |
| SCHEMBL25132999 | 0.80 | FKBP1A (0.54) | KLK7KLK5FKBP1AACEPREP | |
| SCHEMBL31072125 | 0.80 | FKBP1A (0.54) | KLK7KLK5FKBP1AACEPREP | |
| SCHEMBL31365829 | 0.80 | FKBP1A (0.54) | KLK7KLK5FKBP1AACEPREP | |
| Trifluoroacetic Acid SCHEMBL11349940 | 0.79 | ACE (0.53) | ACEDPP4DPP8DPP9DPP7 | |
| Trifluoroacetic Acid SCHEMBL11349935 | 0.79 | ACE (0.53) | ACEDPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4285857-A | Cyclic analogues of callidine | CHIPENS GUNAR I | 1981-08-25 | — | — | US | disclosed |