Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.59 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.59 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL79515 | 0.92 | ALDH1A1 (0.76) | ALDH1A1CYP3A4CA2LMNAHSD17B10 | |
| SCHEMBL30825765 | 0.92 | ALDH1A1 (0.76) | ALDH1A1CYP3A4CA2LMNAHSD17B10 | |
| SCHEMBL27543081 | 0.89 | ALDH1A1 (0.72) | ALDH1A1CYP3A4CA2LMNAHSD17B10 | |
| Benzoic Acid SCHEMBL15789975 | 0.88 | ALDH1A1 (0.70) | ALDH1A1CYP3A4CA2LMNAHSD17B10 | |
| Benzoic Acid SCHEMBL28570741 | 0.88 | ALDH1A1 (0.70) | ALDH1A1CYP3A4CA2LMNAHSD17B10 | |
| SCHEMBL30437742 | 0.88 | PRSS1 (0.74) | ALDH1A1CYP3A4CA2LMNAHSD17B10 | |
| SCHEMBL2825213 | 0.88 | PRSS1 (0.56) | ALDH1A1CYP3A4CA2LMNAHSD17B10 | |
| Bis(2-Ethylhexyl) Phthalate SCHEMBL8372974 | 0.87 | ALDH1A1 (0.82) | ALDH1A1CYP3A4CA2LMNAHSD17B10 | |
| SCHEMBL15286366 | 0.87 | ALDH1A1 (0.68) | ALDH1A1CYP3A4CA2LMNAHSD17B10 | |
| SCHEMBL3320267 | 0.87 | PRSS1 (0.77) | ALDH1A1CYP3A4CA2LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107802379-A | Diamond compact, joint prosthesis and the prosthetic joint component of joint prosthesis | 中科钢研节能科技有限公司 | 2018-03-16 | — | — | CN | disclosed |
| CN-102892386-B | Use of Ti and Nb bonded TiC in artificial joint | DIAMICRON INC | 2015-03-25 | — | — | CN | disclosed |
| US-8603181-B2 | Use of Ti and Nb cemented in TiC in prosthetic joints | Dimicron, Inc (US) | 2013-12-10 | — | — | US | disclosed |
| EP-1253870-B1 | COMPONENT FOR A PROSTHETIC JOINT HAVING A DIAMOND LOAD BEARING AND ARTICULATION SURFACE | DIMICRON INC (US) | 2013-03-13 | — | — | EP | disclosed |
| EP-2555711-A2 | USE OF TI AND NB CEMENTED TIC IN PROSTHETIC JOINTS | Dimicron, Inc. (US) | 2013-02-13 | — | — | EP | disclosed |
| CN-102892386-A | Use of Ti and Nb bonded TiC in artificial joint | DIAMICRON INC | 2013-01-23 | — | — | CN | disclosed |
| CN-1871442-B | Roller bearing assembly | DIAMICRON, INC. (US) | 2012-02-08 | — | — | CN | disclosed |
| WO-2011127321-A2 | USE OF TI AND NB CEMENTED TIC IN PROSTHETIC JOINTS | DIAMICRON, INC. (US) | 2011-10-13 | — | — | WO | disclosed |
| US-8016889-B2 | Articulating diamond-surfaced spinal implants | Diamicron, Inc (US) | 2011-09-13 | — | — | US | disclosed |
| EP-1552173-B1 | Bearings, races and components thereof having diamond and other superhard surfaces | DIAMICRON INC (US) | 2011-02-16 | — | — | EP | disclosed |
| US-6410877-B1 | Methods for shaping and finishing prosthetic joint components including polycrystalline diamond compacts | DIAMICRON, INC. | 2002-06-25 | — | — | US | disclosed |
| US-6402787-B1 | Prosthetic hip joint having at least one sintered polycrystalline diamond compact articulation surface and substrate surface topographical features in said polycrystalline diamond compact | DIAMICRON LENDERS, LLC | 2002-06-11 | — | — | US | disclosed |
| US-6398815-B1 | Prosthetic joint having at least one superhard articulation surface | DIAMICRON, INC. | 2002-06-04 | — | — | US | disclosed |
| US-6290726-B1 | Prosthetic hip joint having sintered polycrystalline diamond compact articulation surfaces | DIAMICRON, INC. | 2001-09-18 | — | — | US | disclosed |
| WO-2001055476-A1 | METHODS FOR MANUFACTURING A DIAMOND PROSTHETIC JOINT COMPONENT | DIAMICRON, INC. (US) | 2001-08-02 | — | — | WO | disclosed |
| WO-2001054627-A1 | SPINE PROSTHESIS HAVING AT LEAST ONE DIAMOND ARTICULATION SURFACE | DIAMICRON, INC. (US) | 2001-08-02 | — | — | WO | disclosed |
| WO-2001054613-A2 | COMPONENT FOR A PROSTHETIC JOINT HAVING A DIAMOND LOAD BEARING AND ARTICULATION SURFACE | DIAMICRON, INC. (US) | 2001-08-02 | — | — | WO | disclosed |
| WO-2001054561-A2 | PROSTHETIC KNEE JOINT | DIAMICRON, INC. (US) | 2001-08-02 | — | — | WO | disclosed |
| WO-2001054628-A1 | A DIAMOND ARTICULATION SURFACE FOR USE IN A PROSTHETIC JOINT | DIAMICRON, INC. (US) | 2001-08-02 | — | — | WO | disclosed |
| WO-2001054612-A2 | PROSTHETIC HIP JOINT HAVING AT LEAST ONE SINTERED POLYCRYSTALLINE DIAMOND COMPACT ARTICULATION SURFACE | DIAMICRON, INC. (US) | 2001-08-02 | — | — | WO | disclosed |