Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.86 |
| ▸ | HTT | P42858 | 1/20 | 0.86 |
| ▸ | AR | P10275 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CDK4 | P11802 | 6/20 | 0.45 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14085644 | 0.94 | HIF1A (0.97) | HIF1AHTTARALDH1A1HPGD | |
| SCHEMBL13851882 | 0.88 | HTT (0.65) | HIF1AHTTARALDH1A1HPGD | |
| SCHEMBL376300 | 0.86 | HIF1A (0.61) | HIF1AHTTARALDH1A1HPGD | |
| SCHEMBL11316310 | 0.86 | HIF1A (0.82) | HIF1AHTTARALDH1A1HPGD | |
| SCHEMBL13513144 | 0.85 | AR (0.78) | HIF1AHTTARALDH1A1KMT2A | |
| SCHEMBL13513140 | 0.84 | AR (0.76) | HIF1AHTTARALDH1A1KMT2A | |
| SCHEMBL19001584 | 0.82 | HTT (0.58) | HIF1AHTTARALDH1A1HPGD | |
| SCHEMBL13513189 | 0.82 | HTT (0.58) | HIF1AHTTARALDH1A1KMT2A | |
| SCHEMBL13513185 | 0.82 | HTT (0.58) | HIF1AHTTARALDH1A1KMT2A | |
| SCHEMBL17702714 | 0.82 | HIF1A (0.56) | HIF1AHTTARALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120184645-A1 | RESINOUS DISPERSIONS INCLUDING AN EPOXY AMINE ADDUCT FOR FLATTING AND RELATED ELECTRODEPOSITABLE COATING COMPOSITIONS | PPG INDUSTRIES OHIO, INC. (US) | 2012-07-19 | — | — | US | disclosed |