Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 12/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1131416 | 1.00 | PTPN1 (0.48) | PTPN1PTPN2CDC25BNR1H4PRMT5 | |
| SCHEMBL1131481 | 0.91 | PTPN1 (0.44) | PTPN1PTPN2CDC25BALDH1A1ALOX5 | |
| SCHEMBL1131573 | 0.91 | PTPN1 (0.44) | PTPN1PTPN2CDC25BALDH1A1ALOX5 | |
| SCHEMBL12860246 | 0.88 | NPSR1 (0.39) | PTPN1PTPN2CDC25BALDH1A1 | |
| SCHEMBL1131258 | 0.83 | ALOX5 (0.41) | PTPN1PRMT5ALDH1A1L3MBTL1ALOX5 | |
| SCHEMBL1131830 | 0.82 | PTPN1 (0.46) | PTPN1PTPN2CDC25BNR1H4PRMT5 | |
| SCHEMBL1131834 | 0.82 | PTPN1 (0.46) | PTPN1PTPN2CDC25BNR1H4PRMT5 | |
| SCHEMBL1131706 | 0.82 | ALOX5 (0.42) | ALDH1A1ALOX5 | |
| SCHEMBL1131710 | 0.82 | ALOX5 (0.42) | ALDH1A1ALOX5 | |
| SCHEMBL1132049 | 0.81 | PTPN11 (0.37) | PTPN1PTPN2CDC25BNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663105-B1 | CYCLOALKYL HETEROCYCLES FOR TREATING HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2011-02-16 | — | — | EP | claimed |
| EP-1663105-B1 | CYCLOALKYL HETEROCYCLES FOR TREATING HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2011-02-16 | — | — | EP | disclosed |