Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | CASP1 | P29466 | 3/20 | 0.47 |
| ▸ | CASP7 | P55210 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11322480 | 0.95 | KDM4E (0.53) | KDM4EHPGDALDH1A1HSD17B10CASP1 | |
| SCHEMBL11334233 | 0.81 | ALDH1A1 (0.48) | KDM4EHPGDALDH1A1HSD17B10CASP1 | |
| SCHEMBL11316606 | 0.80 | KDM4E (0.63) | KDM4EHPGDALDH1A1HSD17B10CASP1 | |
| SCHEMBL24317388 | 0.79 | RXFP1 (0.43) | KDM4EHPGDALDH1A1HSD17B10CASP1 | |
| SCHEMBL24317445 | 0.79 | PDE3B (0.42) | KDM4EHPGDALDH1A1HSD17B10CASP1 | |
| SCHEMBL11319242 | 0.79 | TYMS (0.55) | KDM4EHPGDALDH1A1HSD17B10CASP1 | |
| SCHEMBL24317747 | 0.77 | CYP4F2 (0.45) | KDM4EHPGDALDH1A1HSD17B10CASP1 | |
| SCHEMBL11344636 | 0.75 | ALDH1A1 (0.50) | KDM4EHPGDALDH1A1HSD17B10CASP1 | |
| SCHEMBL11689750 | 0.75 | KDM4E (0.45) | KDM4EHPGDALDH1A1HSD17B10CASP1 | |
| SCHEMBL8481472 | 0.74 | HSD17B10 (0.46) | KDM4EHPGDALDH1A1HSD17B10CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260770-A | Naphtholactam dyes | CIBA-GEIGY AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
| US-4256896-A | THIAZOLE, IMIDAZOLINE, AND OXAZOLINE DYES; DISPERSE DYES; ANIONIC DYES; TEXTILES | CIBA-GEIGY AKTIENGESELLSCHAFT (DE) | 1981-03-17 | — | — | US | disclosed |
| US-4246410-A | BENZINDOLE DYES OF YELLOW AND RED | CIBA -GEIGY AKTIENGESELLSCHAFT (CH) | 1981-01-20 | — | — | US | disclosed |
| US-4246422-A | Naphtholactam dyestuffs | CIBA-GEIGY AG (CH) | 1981-01-20 | — | — | US | disclosed |
| US-4236007-A | YELLOW SHADES ON POLYESTERS | CIBA-GEIGY AKTIENGESELLSCHAFT (CH) | 1980-11-25 | — | — | US | disclosed |
| US-4180665-A | Substituted 3-benz(cd)indol-2-(1H)-ylidene-furo[2,3-b]quinoxalin-2(3H)one dyestuffs | CIBA-GEIGY AKTIENGESELLSCHAFT (CH) | 1979-12-25 | — | — | US | disclosed |
| US-4159379-A | Dispersion dyestuffs of the naphtholactam series | CIBA-GEIGY AG (CH) | 1979-06-26 | — | — | US | disclosed |
| US-4148805-A | POLYESTERS, RED, YELLLOW | CIBA-GEIGY AG (CH) | 1979-04-10 | — | — | US | disclosed |
| US-4146541-A | YELLOW SHADE ON POLYESTERS | CIBA-GEIGY AG (CH) | 1979-03-27 | — | — | US | disclosed |