Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 6/20 | 0.49 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | STS | P08842 | 4/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11325678 | 1.00 | HSD17B3 (0.49) | HSD17B3CES2CES1STSHDAC3 | |
| SCHEMBL11324137 | 1.00 | HSD17B3 (0.49) | HSD17B3CES2CES1STSHDAC3 | |
| SCHEMBL11313632 | 1.00 | HSD17B3 (0.49) | HSD17B3CES2CES1STSHDAC3 | |
| SCHEMBL11679790 | 1.00 | HSD17B3 (0.49) | HSD17B3CES2CES1STSHDAC3 | |
| SCHEMBL8391805 | 0.94 | HSD17B3 (0.59) | HSD17B3 | |
| SCHEMBL8390621 | 0.94 | HSD17B3 (0.59) | HSD17B3 | |
| SCHEMBL8391661 | 0.94 | HSD17B3 (0.59) | HSD17B3 | |
| SCHEMBL8626758 | 0.94 | HSD17B3 (0.59) | HSD17B3 | |
| SCHEMBL11325230 | 0.93 | HDAC3 (0.47) | HSD17B3CES2CES1STSHDAC3 | |
| SCHEMBL3125344 | 0.92 | CES2 (0.55) | CES2CES1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4035325-A | ANTIMONY, SUBSTITUTED HYDRAZINE OR 3-AMINO-1,2,4-TRIAZOLE AMIDE ION | STANDARD OIL COMPANY (INDIANA) (US) | 1977-07-12 | — | — | US | claimed |
| US-4306930-A | INCORPORATING A HYDRAZIDE OR DIHYDRAZIDE AND THEN VULCANIZING IN CONTACT WITH A METAL | CIBA-GEIGY CORPORATION (US) | 1981-12-22 | — | — | US | disclosed |
| US-4077948-A | N-SALICYLIDENE-N*-SALICYLHYDRAZIDES | CIBA-GEIGY CORPORATION (US) | 1978-03-07 | — | — | US | disclosed |
| US-4038247-A | STABILIZING POLYOLEFINS WITH DIACYL DIHYDRAZIDES | CIBA-GEIGY CORPORATION (US) | 1977-07-26 | — | — | US | disclosed |
| US-4035325-A | ANTIMONY, SUBSTITUTED HYDRAZINE OR 3-AMINO-1,2,4-TRIAZOLE AMIDE ION | STANDARD OIL COMPANY (INDIANA) (US) | 1977-07-12 | — | — | US | disclosed |
| US-3994987-A | Metal deactivators as adhesion promotors for vulcanizable elastomers to metals | CIBA-GEIGY CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |