Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1132420 | 0.91 | PDGFRB (0.73) | PDGFRBPDGFRA | |
| SCHEMBL1132499 | 0.89 | PDGFRB (0.75) | PDGFRBPDGFRA | |
| SCHEMBL1132416 | 0.88 | PDGFRB (0.60) | PDGFRBPDGFRA | |
| SCHEMBL6710982 | 0.87 | PDGFRB (0.56) | PDGFRBPDGFRA | |
| SCHEMBL2388345 | 0.86 | PDGFRB (0.74) | PDGFRBPDGFRA | |
| SCHEMBL6709661 | 0.86 | PDGFRB (0.75) | PDGFRBPDGFRA | |
| SCHEMBL1132325 | 0.86 | PDGFRB (0.64) | PDGFRBPDGFRA | |
| SCHEMBL1131894 | 0.86 | PDGFRB (0.57) | PDGFRBPDGFRA | |
| SCHEMBL2389482 | 0.86 | PDGFRB (0.58) | PDGFRBPDGFRA | |
| SCHEMBL2390551 | 0.85 | PDGFRB (0.74) | PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022071-B2 | Nitrogenous heterocyclic compounds | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-09-20 | — | — | US | claimed |
| EP-1309568-B1 | [(quinazolin-4-yl)piperazin-4-yl]thiocarboxamide compounds as inhibitors of the phosphorylation of a PDGF receptor | MILLENNIUM PHARM INC (US) | 2011-02-16 | — | — | EP | claimed |
| EP-1309568-A2 | NITROGENOUS HETEROCYCLIC COMPOUNDS | Millennium Pharmaceuticals, Inc. (US) | 2003-05-14 | — | — | EP | claimed |
| WO-2002016361-A2 | NITROGENOUS HETEROCYCLIC COMPOUNDS | COR THERAPEUTICS, INC. (US) | 2002-02-28 | — | — | WO | claimed |