Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11306317 | 0.94 | KMT2A (0.41) | KMT2APOLBPKMPTPN1PTPN7 | |
| SCHEMBL10538310 | 0.92 | KMT2A (0.40) | KMT2APOLBPKMPTPN1PTPN7 | |
| SCHEMBL22660731 | 0.90 | KMT2A (0.44) | KMT2APOLBPKMPTPN1PTPN7 | |
| SCHEMBL22660732 | 0.90 | KMT2A (0.44) | KMT2APOLBPKMPTPN1PTPN7 | |
| SCHEMBL1933837 | 0.90 | KMT2A (0.44) | KMT2APOLBPKMPTPN1PTPN7 | |
| SCHEMBL6576563 | 0.82 | KMT2A (0.44) | KMT2APOLBPKMPTPN1PTPN7 | |
| SCHEMBL5763409 | 0.81 | — | — | |
| SCHEMBL5761970 | 0.81 | — | — | |
| SCHEMBL5762547 | 0.81 | — | — | |
| SCHEMBL7278342 | 0.80 | KMT2A (0.48) | KMT2APOLBPKMPTPN1PTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4245121-A | HAVING A TERMINAL CYCLIC MOIETY IN THE B-CHAIN | AMERICAN CYANAMID COMPANY (US) | 1981-01-13 | — | — | US | disclosed |
| US-4243817-A | TERMINAL CYCLIC MOIETY IN THE B-CHAIN; PROSTOGLANDIN ACTIVITY | AMERICAN CYANAMID COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| US-4202988-A | Prostenoic acids and esters | AMERICAN CYANAMID COMPANY (US) | 1980-05-13 | — | — | US | disclosed |
| US-4197407-A | PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1980-04-08 | — | — | US | disclosed |
| US-4178456-A | PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1979-12-11 | — | — | US | disclosed |
| US-4131737-A | PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1978-12-26 | — | — | US | disclosed |