Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7292793 | 1.00 | KMT2A (0.48) | KMT2AMEN1TSHRPOLBL3MBTL1 | |
| SCHEMBL7292797 | 1.00 | KMT2A (0.48) | KMT2AMEN1TSHRPOLBL3MBTL1 | |
| SCHEMBL2139138 | 0.94 | KMT2A (0.50) | KMT2AMEN1TSHRPOLBL3MBTL1 | |
| SCHEMBL8716342 | 0.92 | KMT2A (0.52) | KMT2AMEN1TSHRPOLBL3MBTL1 | |
| SCHEMBL20773076 | 0.92 | KMT2A (0.52) | KMT2AMEN1TSHRPOLBL3MBTL1 | |
| SCHEMBL5613043 | 0.92 | KMT2A (0.52) | KMT2AMEN1TSHRPOLBL3MBTL1 | |
| SCHEMBL2828919 | 0.92 | KMT2A (0.52) | KMT2AMEN1TSHRPOLBL3MBTL1 | |
| SCHEMBL22127720 | 0.92 | KMT2A (0.52) | KMT2AMEN1TSHRPOLBL3MBTL1 | |
| SCHEMBL10942351 | 0.90 | TSHR (0.47) | KMT2AMEN1TSHRPOLBL3MBTL1 | |
| SCHEMBL30471428 | 0.82 | KMT2A (0.41) | KMT2AMEN1TSHRPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11116212-B2 | Carbonyl containing compounds for controlling and repelling Cimicidae populations | SEMIOSBIO TECHNOLOGIES INC. (CA) | 2021-09-14 | — | — | US | disclosed |
| US-11116212-B2 | Carbonyl containing compounds for controlling and repelling Cimicidae populations | SEMIOSBIO TECHNOLOGIES INC. (CA) | 2021-09-14 | — | — | US | disclosed |
| CN-107089962-B | A method of maltol and homologue are prepared by molecular oxygen oxidation | 山东新和成药业有限公司 | 2019-09-10 | — | — | CN | disclosed |
| CN-107089962-A | A kind of method that maltol and homologue are prepared by molecular oxygen oxidation | 山东新和成药业有限公司 | 2017-08-25 | — | — | CN | disclosed |
| WO-2012129702-A1 | CARBONYL CONTAINING COMPOUNDS FOR CONTROLLING AND REPELLING CIMICIDAE POPULATIONS | SEMIOSBIO TECHNOLOGIES INC. (CA) | 2012-10-04 | — | — | WO | disclosed |
| US-5389647-A | A prodrugs as hypotensive agents, treating congestive heart failure, urogenital disorders, vision defects | ABBOTT LABORATORIES (US) | 1995-02-14 | — | — | US | disclosed |
| US-5385833-A | Enzymatic synthesis of alcohols from carbonyl compounds | THE SCRIPPS RESEARCH INSTITUTE (US) | 1995-01-31 | — | — | US | disclosed |
| US-5244910-A | Treating hypertension, congestive heart failure | ABBOTT LABORATORIES (US) | 1993-09-14 | — | — | US | disclosed |
| EP-0543936-A4 | RENIN INHIBITORS | — | 1993-06-30 | — | — | EP | disclosed |
| EP-0543936-A1 | RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003429-A1 | RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1992-03-05 | — | — | WO | disclosed |
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |
| US-4496767-A | REARRANGEMENT, ESTERIFICATION AND REDUCTION OF A FURAN-CARBINOL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11116212-B2 | Carbonyl containing compounds for controlling and repelling Cimicidae populations | DDT, AOC1, EGLN1 | KMT2A 798/4885MEN1 3357/4885TSHR 4777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.