Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.45 |
| ▸ | CCNC | P24863 | 10/20 | 0.38 |
| ▸ | CDK8 | P49336 | 10/20 | 0.38 |
| ▸ | HASPIN | Q8TF76 | 9/20 | 0.38 |
| ▸ | CDK19 | Q9BWU1 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11335622 | 0.97 | CNR2 (0.46) | CNR2CCNCCDK8HASPINCDK19 | |
| SCHEMBL11332113 | 0.96 | CNR2 (0.47) | CNR2CCNCCDK8HASPINCDK19 | |
| SCHEMBL11340122 | 0.96 | CNR2 (0.47) | CNR2CCNCCDK8HASPINCDK19 | |
| SCHEMBL11323763 | 0.88 | CNR2 (0.45) | CNR2CCNCCDK8HASPINCDK19 | |
| SCHEMBL11319420 | 0.86 | CCNC (0.41) | CNR2CCNCCDK8HASPINCDK19 | |
| SCHEMBL11323731 | 0.85 | CNR2 (0.38) | CNR2CCNCCDK8HASPINCDK19 | |
| SCHEMBL11321121 | 0.84 | CNR2 (0.46) | CNR2CCNCCDK8HASPINCNR1 | |
| Hydrochloric Acid SCHEMBL11331752 | 0.83 | CCNC (0.34) | CNR2CCNCCDK8HASPINCDK19 | |
| SCHEMBL11323625 | 0.83 | CNR2 (0.51) | CNR2CCNCCDK8HASPINCDK19 | |
| SCHEMBL11323764 | 0.82 | CNR2 (0.46) | CNR2CCNCCDK8HASPINCDK19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4254116-A | ANALGESICS, ANTIDEPRESSANTS, NEUTRALIZING AGENTS | ABBOTT LABORATORIES (US) | 1981-03-03 | — | — | US | disclosed |