Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.45 |
| ▸ | CNR1 | P21554 | 5/20 | 0.37 |
| ▸ | CCNC | P24863 | 7/20 | 0.36 |
| ▸ | CDK8 | P49336 | 7/20 | 0.36 |
| ▸ | HASPIN | Q8TF76 | 6/20 | 0.36 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11335622 | 0.91 | CNR2 (0.46) | CNR2CNR1CCNCCDK8HASPIN | |
| SCHEMBL11340122 | 0.90 | CNR2 (0.47) | CNR2CNR1CCNCCDK8HASPIN | |
| SCHEMBL11332113 | 0.90 | CNR2 (0.47) | CNR2CNR1CCNCCDK8HASPIN | |
| SCHEMBL11323658 | 0.89 | CNR2 (0.43) | CNR2CNR1CCNCCDK8HASPIN | |
| SCHEMBL11319343 | 0.88 | CNR2 (0.45) | CNR2CNR1CCNCCDK8HASPIN | |
| SCHEMBL9285694 | 0.85 | CNR2 (0.45) | CNR2CNR1TRPA1CYP1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL11321217 | 0.84 | CNR2 (0.33) | CNR2CCNCCDK8HASPINCDK19 | |
| Hydrochloric Acid SCHEMBL11321211 | 0.84 | CNR2 (0.33) | CNR2CCNCCDK8HASPINCDK19 | |
| SCHEMBL11332476 | 0.84 | CNR2 (0.34) | CNR2CNR1CCNCCDK8HASPIN | |
| Hydrochloric Acid SCHEMBL11812153 | 0.84 | CNR2 (0.45) | CNR2CNR1TRPA1CYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4254116-A | ANALGESICS, ANTIDEPRESSANTS, NEUTRALIZING AGENTS | ABBOTT LABORATORIES (US) | 1981-03-03 | — | — | US | disclosed |