SCHEMBL1131940

SCHEMBL1131940

COC(=O)[N]CS(=O)(=O)O

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.31
CA14 Q9ULX7 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2489615 0.69
SCHEMBL9704744 0.63
SCHEMBL5637916 0.63 CA12 (0.32) CA12CA14TSHR
SCHEMBL7759281 0.62
SCHEMBL1726876 0.62
SCHEMBL12333357 0.62
SCHEMBL5639056 0.62
SCHEMBL1123070 0.62
SCHEMBL3024985 0.60
SCHEMBL181867 0.60 ALDH1A1 (0.44) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1340762-B1 Cephalosporin synthesis SANDOZ AG (CH) 2011-02-16 EP disclosed
EP-1340762-A1 Cephalosporin synthesis BIOCHEMIE GESELLSCHAFT M.B.H. (AT) 2003-09-03 EP disclosed
EP-0757691-B1 CEPHALOSPORIN SYNTHESIS BIOCHEMIE GMBH (AT) 2003-07-02 EP disclosed
US-6093813-A Cephalosporin compounds BIOCHEMIE GESELLSCHAFT M.B.H. (AT) 2000-07-25 US disclosed
US-6063917-A Cephalosporin synthesis BIOCHEMIE GESELLSCHAFT M.B.H. (AT) 2000-05-16 US disclosed
US-6034237-A 3-imino-cephalosporins BIOCHEMIE GESELLSCHAFT M.B.H. (AT) 2000-03-07 US disclosed
US-5856474-A Cephalosporin synthesis BIOCHEMIE GESELLSCHAFT, M.B.H. (AT) 1999-01-05 US disclosed
EP-0757691-A1 CEPHALOSPORIN SYNTHESIS BIOCHEMIE GESELLSCHAFT M.B.H. (AT) 1997-02-12 EP disclosed
WO-1995029182-A1 CEPHALOSPORIN SYNTHESIS BIOCHEMIE GESELLSCHAFT M.B.H. (AT) 1995-11-02 WO disclosed