Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.71 |
| ▸ | RAB9A | P51151 | 7/20 | 0.71 |
| ▸ | TTR | P02766 | 3/20 | 0.68 |
| ▸ | MAOA | P21397 | 5/20 | 0.60 |
| ▸ | TNKS | O95271 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69937 | 0.92 | NPC1 (0.58) | NPC1RAB9ATTRMAOATNKS | |
| SCHEMBL490247 | 0.91 | TTR (0.68) | NPC1RAB9ATTRMAOATNKS | |
| SCHEMBL11319698 | 0.90 | KDM4E (0.56) | NPC1RAB9ATTRMAOATNKS | |
| SCHEMBL8954225 | 0.89 | TNKS (0.58) | NPC1RAB9ATTRTNKSKMT2A | |
| SCHEMBL20350005 | 0.88 | NPC1 (0.56) | NPC1RAB9ATTRMAOATNKS | |
| SCHEMBL20317213 | 0.87 | NPC1 (0.55) | NPC1RAB9ATTRMAOATNKS | |
| SCHEMBL20329635 | 0.87 | NPC1 (0.54) | NPC1RAB9ATTRMAOATNKS | |
| SCHEMBL20329634 | 0.87 | NPC1 (0.54) | NPC1RAB9ATTRMAOATNKS | |
| SCHEMBL20346586 | 0.85 | NPC1 (0.52) | NPC1RAB9ATTRMAOATNKS | |
| SCHEMBL11866301 | 0.85 | THRB (0.54) | NPC1RAB9ATTRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111057037-B | Ultraviolet light-promoted synthesis method of xanthone compound | 浙江工业大学 | 2021-07-23 | — | — | CN | disclosed |
| CN-111057037-A | Ultraviolet light-promoted synthesis method of xanthone compound | 浙江工业大学 | 2020-04-24 | — | — | CN | disclosed |
| US-4250182-A | Pharmaceutical composition containing acridone compounds and method of using same | BURROUGHS WELLCOME CO. (US) | 1981-02-10 | — | — | US | disclosed |