1,6-Hexanediol

1,6-Hexanediol

SCHEMBL11320508

CC(C)(C)OOC(C)(CC(=O)O)OOC(C)(C)C.CC(C)(C)OOC(C)(CC(=O)O)OOC(C)(C)C.OCCCCCCO

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.44
FFAR1 O14842 2/20 0.41
CPT2 P23786 1/20 0.41
GPR84 Q9NQS5 1/20 0.40
FFAR4 Q5NUL3 1/20 0.40
CYP4F2 P78329 2/20 0.37
CYP4A11 Q02928 2/20 0.37
HMGCR P04035 1/20 0.37
CHRM1 P11229 1/20 0.37
TBXA2R P21731 1/20 0.37
ADRA1A P35348 1/20 0.37
CYP2D6 P10635 1/20 0.35
TSHR P16473 1/20 0.35
CYP2C19 P33261 1/20 0.35
HIF1A Q16665 1/20 0.35
CAMK2A Q9UQM7 1/20 0.33
FNTA P49354 1/20 0.32
FNTB P49356 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ACHE P22303 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL464959 0.88 HMGCR (0.46) TDP1FFAR1CPT2HMGCRCHRM1
Acetic Acid SCHEMBL25274821 0.84 HMGCR (0.42) TDP1FFAR1CPT2HMGCRCHRM1
Di(Hydroxyethyl)Ether SCHEMBL11309228 0.83 TSHR (0.37) TDP1FFAR1CPT2CYP4F2CYP4A11
SCHEMBL11305851 0.82 HMGCR (0.38) TDP1FFAR1CPT2HMGCRCHRM1
Glycerin SCHEMBL11309634 0.79 CYP2C19 (0.39) TDP1FFAR1CPT2HMGCRCHRM1
1,6-Hexanediol SCHEMBL11422342 0.78 TSHR (0.50) TDP1FFAR1GPR84FFAR4CYP4F2
Azelaic Acid SCHEMBL27377315 0.70 TSHR (0.60) TDP1FFAR1GPR84FFAR4TSHR
SCHEMBL11299673 0.70 HMGCR (0.46) TDP1FFAR1CPT2HMGCRCHRM1
SCHEMBL529864 0.69 HMGCR (0.41) TDP1FFAR1CPT2HMGCRCHRM1
SCHEMBL6698390 0.69 FFAR1 (0.83) TDP1FFAR1CPT2GPR84FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4288379-A Hydrocarbon polyl gem-bis(t-alkylperoxy)alkanoates derived from β-keto-acids THE DOW CHEMICAL COMPANY (US) 1981-09-08 US disclosed