Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11782476 | 0.84 | TDP1 (0.40) | TSHRTDP1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL11422339 | 0.82 | TDP1 (0.38) | TSHRTDP1ALDH1A1LMNAHSD17B10 | |
| 1,6-Hexanediol SCHEMBL27903227 | 0.79 | TSHR (0.56) | TSHRTDP1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL9978560 | 0.78 | CYP4F2 (0.39) | TSHRTDP1ALDH1A1LMNAHSD17B10 | |
| 1,4-Butanediol SCHEMBL28392323 | 0.78 | SMN1; SMN2 (0.42) | TSHRTDP1ALDH1A1LMNAHSD17B10 | |
| 1,6-Hexanediol SCHEMBL27381760 | 0.76 | ALDH1A1 (0.53) | TSHRTDP1ALDH1A1LMNAHSD17B10 | |
| Alcohol SCHEMBL9770103 | 0.76 | TSHR (0.61) | TSHRTDP1ALDH1A1 | |
| SCHEMBL21242384 | 0.75 | CYP4F2 (0.44) | TSHRTDP1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL31069047 | 0.75 | TDP1 (0.35) | TSHRTDP1ALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL27050941 | 0.75 | CYP4F2 (0.44) | TSHRTDP1ALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4218548-A | Peroxy compounds and vulcanizable compositions thereof | PENNWALT CORPORATION (US) | 1980-08-19 | — | — | US | disclosed |
| US-4180518-A | CROSSLINKING OR VULCANIZING AGENTS | PENNWALT CORPORATION (US) | 1979-12-25 | — | — | US | disclosed |
| US-4177204-A | AGENTS FOR CROSSLINKING OR VULCANIZING POLYMERS | PENNWALT CORPORATION (US) | 1979-12-04 | — | — | US | disclosed |
| US-4129700-A | Peroxy compounds and vulcanizable compositions thereof | PENNWALT CORPORATION (US) | 1978-12-12 | — | — | US | disclosed |