Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD40 | P25942 | 1/20 | 0.57 |
| ▸ | CD40LG | P29965 | 1/20 | 0.57 |
| ▸ | ENPP2 | Q13822 | 10/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.51 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.51 |
| ▸ | EP300 | Q09472 | 1/20 | 0.51 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973057 | 0.88 | ENPP2 (0.54) | CD40CD40LGENPP2PRMT1PRMT3 | |
| SCHEMBL8972450 | 0.84 | ENPP2 (0.56) | CD40CD40LGENPP2PRMT1PRMT3 | |
| SCHEMBL11303228 | 0.82 | CD40 (0.51) | CD40CD40LGENPP2PRMT1PRMT3 | |
| SCHEMBL8972663 | 0.82 | ENPP2 (0.53) | CD40CD40LGENPP2PRMT1PRMT3 | |
| SCHEMBL14493336 | 0.79 | ENPP2 (0.55) | CD40CD40LGENPP2PRMT1ALDH1A1 | |
| SCHEMBL20746879 | 0.77 | ENPP2 (0.61) | CD40CD40LGENPP2PRMT1PRMT3 | |
| SCHEMBL11315827 | 0.77 | CD40 (0.45) | CD40CD40LGENPP2PRMT1PRMT3 | |
| SCHEMBL17277636 | 0.77 | CD40 (0.74) | CD40CD40LGENPP2PRMT1PRMT3 | |
| SCHEMBL8972650 | 0.76 | ENPP2 (0.46) | CD40CD40LGENPP2PRMT1PRMT3 | |
| SCHEMBL13014584 | 0.76 | CD40 (0.59) | CD40CD40LGENPP2PRMT1PRMT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4263206-A | Reactive dyestuffs containing chlorine or fluorine substituents and one or more 1,3-dicyanobenzene radicals linked to the dyestuff at the 2-, 4- or 6-position | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-04-21 | — | — | US | disclosed |
| US-4213899-A | FOR CELLULOSE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-07-22 | — | — | US | disclosed |