SCHEMBL11322360

SCHEMBL11322360

O=CNCCCCCCCCCCCCNC=O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 6/20 0.72
ADH1A P07327 6/20 0.72
ADH7 P40394 5/20 0.72
ADH1C P00326 5/20 0.72
ADH4 P08319 2/20 0.72
EPHX1 P07099 1/20 0.72
HIF1A Q16665 2/20 0.35
KDM1A O60341 1/20 0.33
TSHR P16473 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MAPK1 P28482 1/20 0.32
ALDH1A1 P00352 2/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
GNAI3 P08754 1/20 0.30
GNAO1 P09471 1/20 0.30
GNAI1 P63096 1/20 0.30
MEN1 O00255 1/20 0.30
CA12 O43570 1/20 0.30
F13A1 P00488 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8764004 1.00 ADH1B (0.72) ADH1BADH1AADH7ADH1CADH4
SCHEMBL11138833 1.00 ADH1B (0.72) ADH1BADH1AADH7ADH1CADH4
SCHEMBL11136512 1.00 ADH1B (0.72) ADH1BADH1AADH7ADH1CADH4
SCHEMBL979732 1.00 ADH1B (0.72) ADH1BADH1AADH7ADH1CADH4
SCHEMBL5104034 0.96 ADH1B (0.68) ADH1BADH1AADH7ADH1CADH4
SCHEMBL8068062 0.96 ADH1B (0.71) ADH1BADH1AADH7ADH1CADH4
SCHEMBL8763225 0.92
SCHEMBL10947273 0.90 ADH1B (0.62) ADH1BADH1AADH7ADH1CADH4
SCHEMBL5967504 0.87 ADH1B (0.59) ADH1BADH1AADH7ADH1CADH4
SCHEMBL17128629 0.87 ADH1B (0.59) ADH1BADH1AADH7ADH1CADH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4251422-A Coating compositions containing polymers with isocyano groups and alkylboranes E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-02-17 US disclosed
US-4251421-A CROSSLINKABLE FILM-FORMING PRIMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-02-17 US disclosed