Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 16/20 | 0.69 |
| ▸ | PDE3A | Q14432 | 16/20 | 0.69 |
| ▸ | PDE4A | P27815 | 4/20 | 0.64 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.64 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.64 |
| ▸ | GALR3 | O60755 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11088031 | 0.84 | PDE3B (0.50) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10644858 | 0.84 | PDE3B (0.53) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10902917 | 0.83 | PDE3B (0.79) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL11089162 | 0.82 | PDE4A (0.52) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10902870 | 0.82 | PDE3B (1.00) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10353457 | 0.81 | PDE3B (0.71) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10625965 | 0.81 | PDE3B (1.00) | PDE3BPDE3APDE4APDE4BPDE4C | |
| Bemoradan SCHEMBL121664 | 0.80 | PDE3B (1.00) | PDE3BPDE3APDE4APDE4BPDE4C | |
| Bemoradan SCHEMBL29605229 | 0.80 | PDE3B (1.00) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL16156959 | 0.79 | PDE3B (1.00) | PDE3BPDE3APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258185-A | HYPOTENSIVE, ANTITHROMBOTIC AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1981-03-24 | — | — | US | disclosed |