Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALPL | P05186 | 1/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | ALPG | P10696 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11323476 | 1.00 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2KDM4EHSD17B10NPC1 | |
| SCHEMBL10765557 | 0.86 | SMN1; SMN2 (0.63) | ALDH1A1SMN1; SMN2KDM4EHSD17B10NPC1 | |
| SCHEMBL10873062 | 0.86 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2KDM4EHSD17B10KMT2A | |
| SCHEMBL13116580 | 0.86 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2KDM4EHSD17B10NPC1 | |
| SCHEMBL8549718 | 0.84 | HSD17B10 (0.61) | ALDH1A1SMN1; SMN2KDM4EHSD17B10RAB9A | |
| SCHEMBL14694121 | 0.84 | HSD17B10 (0.61) | ALDH1A1SMN1; SMN2KDM4EHSD17B10NPC1 | |
| SCHEMBL8549726 | 0.84 | HSD17B10 (0.61) | ALDH1A1SMN1; SMN2KDM4EHSD17B10RAB9A | |
| SCHEMBL5711200 | 0.84 | MBTPS1 (0.67) | ALDH1A1SMN1; SMN2KDM4EHSD17B10NPC1 | |
| SCHEMBL11324889 | 0.84 | MBTPS1 (0.67) | ALDH1A1SMN1; SMN2KDM4EHSD17B10NPC1 | |
| SCHEMBL26616368 | 0.84 | CYP1A2 (0.58) | ALDH1A1SMN1; SMN2KDM4EHSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4252952-A | 7-(α-Substituted glycinamido)-3-substituted methyl-3-cephem-4-carboxylic acids and their derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-02-24 | — | — | US | disclosed |
| US-4178445-A | 7-(α-Substituted glycinamido)-3-substituted methyl-3-cephem-4-carboxylic acids and their derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1979-12-11 | — | — | US | disclosed |
| US-4039536-A | 7-(α-SUBSTITUTED GLYCINAMIDO)-3-SUBSTITUTED METHYL-3-CEPHEM-4-CARBOXYLIC ACIDS AND THEIR DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-08-02 | — | — | US | disclosed |