Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 8/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.62 |
| ▸ | PGR | P06401 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.61 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 3/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | MLNR | O43193 | 1/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11323632 | 1.00 | NR3C1 (0.63) | NR3C1CYP3A4HIF1ALMNACYP2C9 | |
| SCHEMBL11323634 | 1.00 | NR3C1 (0.63) | NR3C1CYP3A4HIF1ALMNACYP2C9 | |
| SCHEMBL11689579 | 0.93 | NR3C1 (0.69) | NR3C1CYP3A4HIF1ALMNACYP2C9 | |
| SCHEMBL11813525 | 0.93 | NR3C1 (0.69) | NR3C1CYP3A4HIF1ALMNACYP2C9 | |
| SCHEMBL11690649 | 0.93 | NR3C1 (0.69) | NR3C1CYP3A4HIF1ALMNACYP2C9 | |
| SCHEMBL8859709 | 0.87 | NR3C1 (0.74) | NR3C1CYP3A4HIF1ALMNACYP2C9 | |
| SCHEMBL11228768 | 0.86 | NR3C1 (0.69) | NR3C1CYP3A4HIF1ALMNACYP2C9 | |
| SCHEMBL9797354 | 0.85 | HIF1A (0.78) | NR3C1CYP3A4HIF1ALMNACYP2C9 | |
| SCHEMBL9797346 | 0.85 | HIF1A (0.78) | NR3C1CYP3A4HIF1ALMNACYP2C9 | |
| SCHEMBL11309009 | 0.85 | HIF1A (0.78) | NR3C1CYP3A4HIF1ALMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257969-A | ANTIINFLAMMATORY STEROIDS | E. R. SQUIBB & SONS, INC. (US) | 1981-03-24 | — | — | US | disclosed |