SCHEMBL1132370

SCHEMBL1132370

O=CC(=O)NN(CC(=O)O)CC(=O)O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.35
EYA2 O00167 1/20 0.35
APP P05067 1/20 0.35
ACE P12821 1/20 0.35
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
CHRM2 P08172 1/20 0.33
ADRA2A P08913 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
DRD1 P21728 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
CYP2C19 P33261 1/20 0.33
ADRA1A P35348 1/20 0.33
DRD3 P35462 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
SLC6A3 Q01959 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13401866 0.70 TDP1 (0.38) TDP1EYA2APPACEKDM4E
SCHEMBL177769 0.70 TDP1 (0.38) TDP1EYA2APPACEKDM4E
SCHEMBL27531095 0.67 TDP1 (0.35) TDP1EYA2APPACEKDM4E
SCHEMBL12687930 0.66 AKT1 (0.42) TDP1
SCHEMBL27696748 0.66 TDP1 (0.43) TDP1EYA2APPACEKDM4E
SCHEMBL7591689 0.65 TDP1 (0.34) TDP1EYA2APPACEKDM4E
SCHEMBL2804362 0.64 TDP1 (0.41) TDP1EYA2APPACEKDM4E
SCHEMBL6982581 0.62
SCHEMBL8998478 0.60
Nitrilotriacetic Acid SCHEMBL10816074 0.60 TDP1 (0.58) TDP1EYA2APPACEKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6706526-B2 ETHYLENEDIAMINE TETRAACETIC ACID OR DERIVATIVE, 5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE, 2-METHYL-4-ISOTHIAZOLIN-3-ONE AND 5-BROMO-5-NITRO-1,3-DIOXANE COULTER INTERNATIONAL CORP. 2004-03-16 US claimed
US-20030166290-A1 Low formaldehyde producing blood diluent COULTER INTERNATIONAL CORP. 2003-09-04 US claimed
US-5834315-A COMPRISING A LYSING AGENT OF A QUATERNARY AMMONIUM AND/OR PYRIDINIUM SALT AND A REDUCING AGENT TO PRODUCE A HEMOCHROMOGEN COULTER CORPORATION (US) 1998-11-10 US claimed
EP-4325210-A1 COMPOSITION, STABILIZATION METHOD, METHOD FOR MEASURING AMOUNT OF LUMINESCENCE, AND STABILIZER FOR LUMINESCENT SUBSTRATE FUJIFILM Corporation (JP) 2024-02-21 EP disclosed
US-20240043742-A1 COMPOSITION, STABILIZATION METHOD, METHOD FOR MEASURING AMOUNT OF LUMINESCENCE, AND STABILIZER FOR LUMINESCENT SUBSTRATE FUJIFILM CORPORATION (JP) 2024-02-08 US disclosed
US-11835532-B2 Green concentrated reagent for hemotology systems BECKMAN COULTER, INC. (US) 2023-12-05 US disclosed
EP-4279924-A1 ADSORPTION INHIBITOR FOR HEPCIDIN, METHOD FOR INHIBITING ADSORPTION, REFERENCE STANDARD, REAGENT, KIT AND MEASUREMENT METHOD FUJIFILM Corporation (JP) 2023-11-22 EP disclosed
US-20230358753-A1 HEPCIDIN ADSORPTION INHIBITOR, METHOD OF INHIBITING ADSORPTION, STANDARD PRODUCT, REAGENT, KIT, AND MEASURING METHOD FUJIFILM CORPORATION (JP) 2023-11-09 US disclosed
EP-3794346-B1 GREEN CONCENTRATED REAGENT FOR HEMATOLOGY SYSTEMS BECKMAN COULTER INC (US) 2023-03-08 EP disclosed
US-20230047876-A1 GREEN CONCENTRATED REAGENT FOR HEMOTOLOGY SYSTEMS BECKMAN COULTER, INC. 2023-02-16 US disclosed
US-11519921-B2 Green concentrated reagent for hematology systems BECKMAN COULTER, INC. (US) 2022-12-06 US disclosed
EP-1426819-A2 Concentrated bleach-fixer composition for silver halide color photographic material KONICA MINOLTA HOLDINGS, INC. (JP) 2004-06-09 EP disclosed
US-6706526-B2 ETHYLENEDIAMINE TETRAACETIC ACID OR DERIVATIVE, 5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE, 2-METHYL-4-ISOTHIAZOLIN-3-ONE AND 5-BROMO-5-NITRO-1,3-DIOXANE COULTER INTERNATIONAL CORP. 2004-03-16 US disclosed
US-20030166290-A1 Low formaldehyde producing blood diluent COULTER INTERNATIONAL CORP. 2003-09-04 US disclosed
EP-0794435-B1 Cyanide-free reagent and method for hemoglobin determination and leukocyte differentiation COULTER INT CORP (US) 2003-01-02 EP disclosed
EP-1241522-A1 Processing method for silver halide color photographic material Fuji Photo Film Co., Ltd. (JP) 2002-09-18 EP disclosed
US-5890028-A Apparatus for and method of development processing FUJI PHOTO FILM CO., LTD. (JP) 1999-03-30 US disclosed
US-5834315-A COMPRISING A LYSING AGENT OF A QUATERNARY AMMONIUM AND/OR PYRIDINIUM SALT AND A REDUCING AGENT TO PRODUCE A HEMOCHROMOGEN COULTER CORPORATION (US) 1998-11-10 US disclosed
US-5801813-A Image recording method and apparatus FUJI PHOTO FILM CO., LTD. (JP) 1998-09-01 US disclosed
EP-0794435-A1 Cyanide-free reagent and method for hemoglobin determination and leukocyte differentiation Coulter International Corp. (US) 1997-09-10 EP disclosed