⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5180442 | 0.84 | — | — | |
| SCHEMBL2185699 | 0.75 | TDP1 (0.43) | — | |
| SCHEMBL13496940 | 0.73 | — | — | |
| SCHEMBL1148010 | 0.73 | — | — | |
| Hadacidin SCHEMBL2115651 | 0.73 | — | — | |
| SCHEMBL207502 | 0.71 | — | — | |
| SCHEMBL8047672 | 0.71 | — | — | |
| SCHEMBL10884385 | 0.71 | — | — | |
| SCHEMBL5778712 | 0.69 | TDP1 (0.45) | — | |
| SCHEMBL20529777 | 0.69 | FFAR3 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111944749-A | Preparation method of human adipose-derived mesenchymal stem cell exosome for treating myocardial infarction | 福建医科大学附属协和医院 | 2020-11-17 | — | — | CN | disclosed |
| CN-111944748-A | high-IL-10-expression human adipose-derived mesenchymal stem cell exosome for treating myocardial infarction and application thereof | 福建医科大学附属协和医院 | 2020-11-17 | — | — | CN | disclosed |
| CN-111944747-A | Human adipose-derived mesenchymal stem cell exosome for treating myocardial infarction and application thereof | 福建医科大学附属协和医院 | 2020-11-17 | — | — | CN | disclosed |
| CN-111925983-A | Preparation method of high-IL-10-expression human adipose-derived mesenchymal stem cell exosome for treating myocardial infarction | 福建医科大学附属协和医院 | 2020-11-13 | — | — | CN | disclosed |
| EP-0433034-B1 | Method involving thermally sensitive alpha-amidoacetyl or beta-amidopropionyl linkages | MINNESOTA MINING & MFG (US) | 1996-09-11 | — | — | EP | disclosed |