Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | MC3R | P41968 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 8/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 8/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27893222 | 0.84 | HCAR2 (0.40) | MKNK1MKNK2TDP1LMNA | |
| SCHEMBL31751769 | 0.76 | TBXAS1 (0.40) | DYRK1ACLK1LMNATBXAS1AURKA | |
| SCHEMBL31061962 | 0.75 | SIRT2 (0.50) | SIRT3F7F3SARM1SIRT2 | |
| SCHEMBL27154339 | 0.75 | GRM5 (0.47) | MAP4K4TBXAS1 | |
| SCHEMBL24159189 | 0.72 | CDC7 (0.38) | SIRT3F7F3SARM1SIRT2 | |
| SCHEMBL29986327 | 0.72 | TBXAS1 (0.48) | SIRT3F7F3SARM1SIRT2 | |
| SCHEMBL28000254 | 0.72 | CLK1 (0.33) | DYRK1ACLK1MKNK1MKNK2 | |
| SCHEMBL1421391 | 0.71 | CHRNA7 (0.48) | DYRK1ACLK1TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL30204477 | 0.71 | TBXAS1 (0.47) | SIRT3F7F3SARM1SIRT2 | |
| Hydrochloric Acid SCHEMBL1421587 | 0.70 | CHRNA7 (0.47) | DYRK1ACLK1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102844318-B | Be used for the treatment of the compound of respiratory syncytial virus infection | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2016-04-13 | — | — | CN | claimed |
| EP-2665727-A1 | BICYCLIC CARBOXAMIDE INHIBITORS OF KINASES | Abbvie Inc. (US) | 2013-11-27 | — | — | EP | claimed |
| CN-102844318-A | Compounds for treating respiratory syncytial virus infections | BIOTA SCIENT MAN | 2012-12-26 | — | — | CN | claimed |
| WO-2012097684-A1 | BICYCLIC CARBOXAMIDE INHIBITORS OF KINASES | ABBOTT LABORATORIES (US) | 2012-07-26 | — | — | WO | claimed |
| WO-2024044098-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-29 | — | — | WO | disclosed |
| CN-102844318-B | Be used for the treatment of the compound of respiratory syncytial virus infection | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2016-04-13 | — | — | CN | disclosed |
| CN-102844318-A | Compounds for treating respiratory syncytial virus infections | BIOTA SCIENT MAN | 2012-12-26 | — | — | CN | disclosed |