Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 9/20 | 0.46 |
| ▸ | FUT8 | Q9BYC5 | 1/20 | 0.45 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CD40 | P25942 | 1/20 | 0.41 |
| ▸ | CD40LG | P29965 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779895 | 0.91 | CYP1A2 (0.54) | CYP1A2CYP2C9MAPK1DNASE1L3ENPP2 | |
| SCHEMBL10394785 | 0.90 | CYP1A2 (0.50) | CYP1A2CYP2C9MAPK1DNASE1L3ENPP2 | |
| SCHEMBL8779901 | 0.86 | FUT8 (0.59) | CYP1A2CYP2C9MAPK1DNASE1L3ENPP2 | |
| SCHEMBL11303228 | 0.85 | CD40 (0.51) | CYP1A2CYP2C9MAPK1DNASE1L3ENPP2 | |
| SCHEMBL10392575 | 0.84 | ENPP2 (0.55) | CYP1A2CYP2C9MAPK1DNASE1L3ENPP2 | |
| SCHEMBL14415198 | 0.84 | CYP1A2 (0.53) | CYP1A2CYP2C9MAPK1DNASE1L3ENPP2 | |
| SCHEMBL11315827 | 0.83 | CD40 (0.45) | CYP1A2CYP2C9MAPK1DNASE1L3ENPP2 | |
| SCHEMBL11306748 | 0.83 | PRMT1 (0.54) | CYP1A2CYP2C9MAPK1DNASE1L3ENPP2 | |
| SCHEMBL8779959 | 0.82 | ENPP2 (0.63) | CYP1A2CYP2C9MAPK1DNASE1L3ENPP2 | |
| SCHEMBL8779919 | 0.82 | CYP1A2 (0.51) | CYP1A2CYP2C9MAPK1DNASE1L3ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4263206-A | Reactive dyestuffs containing chlorine or fluorine substituents and one or more 1,3-dicyanobenzene radicals linked to the dyestuff at the 2-, 4- or 6-position | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-04-21 | — | — | US | disclosed |
| US-4213899-A | FOR CELLULOSE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-07-22 | — | — | US | disclosed |