Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.64 |
| ▸ | MAOB | P27338 | 2/20 | 0.60 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3359780 | 0.81 | MAOB (0.80) | AKR1B1MAOBSLC2A1KMT2AMEN1 | |
| SCHEMBL30285083 | 0.81 | MAOB (0.80) | AKR1B1MAOBSLC2A1KMT2AMEN1 | |
| SCHEMBL8117451 | 0.80 | AKR1B1 (0.78) | AKR1B1MAOBSLC2A1MAPK1KMT2A | |
| SCHEMBL8827849 | 0.80 | AKR1B1 (0.78) | AKR1B1MAOBSLC2A1MAPK1KMT2A | |
| SCHEMBL20876884 | 0.80 | MAOB (0.78) | AKR1B1MAOBSLC2A1KMT2AMEN1 | |
| SCHEMBL31047782 | 0.80 | MAOB (0.78) | AKR1B1MAOBSLC2A1KMT2AMEN1 | |
| SCHEMBL6869618 | 0.80 | AKR1B1 (0.48) | AKR1B1MAOBSLC2A1MAPK1KMT2A | |
| SCHEMBL11329370 | 0.79 | KDM4E (0.43) | AKR1B1MAOBKMT2AGAAKDM4E | |
| SCHEMBL4250015 | 0.78 | AKR1B1 (0.76) | AKR1B1MAOBSLC2A1MAPK1KMT2A | |
| SCHEMBL29495537 | 0.78 | AKR1B1 (1.00) | AKR1B1MAOBSLC2A1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4289779-A | HETEROCYCLIC ESTERS OF MONIC ACID; TREATMENT OF PENICILLIN-RESISTANT GONORRHEA | BEECHAM GROUP LIMITED (GB) | 1981-09-15 | — | — | US | claimed |
| US-4267316-A | HETEROCYCLIC ESTERS OF PSEUDOMONIC ACID; UROGENITAL DISORDERS; NEISSERIA; BRONCHIUS; VETERINARY MEDICINE | BEECHAM GROUP LIMITED (GB) | 1981-05-12 | — | — | US | claimed |