SCHEMBL11325002

SCHEMBL11325002

O=P(O)(O)Oc1ccon1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 10/20 0.43
INPP5A Q14642 6/20 0.43
AKT1 P31749 1/20 0.43
INPP5B P32019 2/20 0.41
SRC P12931 6/20 0.39
KDM4E B2RXH2 2/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
USP2 O75604 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
PDE3A Q14432 1/20 0.32
HSD17B10 Q99714 1/20 0.32
BLM P54132 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27602768 0.98 INPPL1 (0.42) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL11378220 0.70
SCHEMBL28178444 0.68 LMNA (0.39) KDM4EALDH1A1HPGDHSD17B10BLM
SCHEMBL7563047 0.68
SCHEMBL9093356 0.68
SCHEMBL9751421 0.67
SCHEMBL8431048 0.67
SCHEMBL11346091 0.67
SCHEMBL2844671 0.66
SCHEMBL2127534 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118047809-A Intermediate 3-amino isoxazole phosphate for preparing MRX-4 and preparation method thereof 浙江安诺和生物医药有限公司 2024-05-17 CN claimed
CN-118047809-A Intermediate 3-amino isoxazole phosphate for preparing MRX-4 and preparation method thereof 浙江安诺和生物医药有限公司 2024-05-17 CN disclosed
CN-118047809-A Intermediate 3-amino isoxazole phosphate for preparing MRX-4 and preparation method thereof 浙江安诺和生物医药有限公司 2024-05-17 CN disclosed
CN-118047809-A Intermediate 3-amino isoxazole phosphate for preparing MRX-4 and preparation method thereof 浙江安诺和生物医药有限公司 2024-05-17 CN disclosed
CN-117567338-A Novel heteroaryl triazole compounds as pesticides 拜耳公司 2024-02-20 CN disclosed
CN-112771034-B Heteroaryl azole compound and pest control agent 日本曹达株式会社 2024-02-09 CN disclosed
CN-112930339-B (hetero) arylimidazole compound and pest control agent 日本曹达株式会社 2023-11-03 CN disclosed
EP-0061037-A1 Fungicides based on 1,2-oxazolyl phosphates, and the use of these active agents in combating fungi BASF Aktiengesellschaft (DE) 1982-09-29 EP disclosed