Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12928826 | 0.89 | TSHR (0.61) | TSHRHPGDALDH1A1CYP3A4DNM1 | |
| SCHEMBL12928822 | 0.88 | TSHR (0.52) | TSHRHPGDALDH1A1CYP3A4DNM1 | |
| SCHEMBL12928825 | 0.88 | TSHR (0.52) | TSHRHPGDALDH1A1CYP3A4DNM1 | |
| SCHEMBL11314449 | 0.86 | TSHR (0.47) | TSHRHPGDALDH1A1CYP3A4DNM1 | |
| SCHEMBL1673486 | 0.84 | TSHR (0.79) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL223929 | 0.84 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL28208975 | 0.84 | TSHR (0.79) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL12120249 | 0.84 | DGKA (0.55) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL12928838 | 0.83 | TSHR (0.61) | TSHRHPGDALDH1A1CYP3A4DNM1 | |
| SCHEMBL12928837 | 0.83 | TSHR (0.61) | TSHRHPGDALDH1A1CYP3A4DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4277319-A | N-SUBSTITUTED ACRYOYLOXYETHYLAMINES | ROHM AND HAAS COMPANY (US) | 1981-07-07 | — | — | US | disclosed |
| US-4115232-A | ACTINIC RADIATION | ROHM AND HAAS COMPANY (US) | 1978-09-19 | — | — | US | disclosed |
| US-4001304-A | RADIATION CURABLE COATINGS | ROHM AND HAAS COMPANY (US) | 1977-01-04 | — | — | US | disclosed |