Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533414 | 0.89 | CYP3A4 (0.42) | CYP3A4TSHRTDP1MAPK1ALDH1A1 | |
| SCHEMBL11325113 | 0.86 | CYP3A4 (0.40) | CYP3A4TSHRTDP1MAPK1ALDH1A1 | |
| SCHEMBL180952 | 0.85 | TSHR (0.45) | CYP3A4TSHRTDP1MAPK1ALDH1A1 | |
| SCHEMBL9859153 | 0.83 | CYP3A4 (0.44) | CYP3A4TSHRTDP1MAPK1TRPA1 | |
| SCHEMBL11686470 | 0.81 | TSHR (0.39) | CYP3A4TSHRTDP1MAPK1ALDH1A1 | |
| SCHEMBL8136787 | 0.80 | TSHR (0.41) | CYP3A4TSHRTDP1MAPK1ALDH1A1 | |
| SCHEMBL7357034 | 0.80 | KIF11 (0.45) | CYP3A4TSHRMAPTNOS3NOS1 | |
| SCHEMBL11531903 | 0.80 | MAPK1 (0.40) | CYP3A4TSHRTDP1MAPK1TRPA1 | |
| SCHEMBL10960028 | 0.80 | TSHR (0.38) | CYP3A4TSHRTDP1MAPK1ALDH1A1 | |
| SCHEMBL10720388 | 0.79 | CYP3A4 (0.44) | CYP3A4TSHRTDP1MAPK1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007541-B1 | SUBSTITUTED 5-PHENYLCARBAMOYL-BARBITURIC ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES | BAYER AG (DE) | 1981-09-09 | — | — | EP | disclosed |
| US-4239762-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-16 | — | — | US | disclosed |
| EP-0007541-A1 | Substituted 5-phenylcarbamoyl-barbituric acids, process for their preparation and their use as insecticides | BAYER AG (DE) | 1980-02-06 | — | — | EP | disclosed |
| US-4140792-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |