Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11363034 | 0.94 | NPSR1 (0.52) | NPSR1ALDH1A1POLBKMT2ANPC1 | |
| SCHEMBL11363030 | 0.94 | NPSR1 (0.52) | NPSR1ALDH1A1POLBKMT2ANPC1 | |
| SCHEMBL6354517 | 0.86 | NPSR1 (0.58) | NPSR1ALDH1A1POLBKMT2ANPC1 | |
| SCHEMBL310005 | 0.80 | NPSR1 (0.64) | NPSR1ALDH1A1POLBKMT2ANPC1 | |
| SCHEMBL9456609 | 0.80 | NPSR1 (0.64) | NPSR1ALDH1A1POLBKMT2ANPC1 | |
| SCHEMBL1270501 | 0.76 | NPSR1 (0.58) | NPSR1ALDH1A1POLBKMT2ANPC1 | |
| SCHEMBL3068205 | 0.75 | NPSR1 (0.64) | NPSR1ALDH1A1POLBKMT2ANPC1 | |
| SCHEMBL812818 | 0.74 | NPSR1 (1.00) | NPSR1ALDH1A1POLBKMT2ANPC1 | |
| SCHEMBL19778 | 0.74 | NPSR1 (0.70) | NPSR1ALDH1A1POLBKMT2ANPC1 | |
| SCHEMBL195179 | 0.73 | NPSR1 (0.54) | NPSR1ALDH1A1POLBKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4279921-A | Dichloromaleic acid diamide derivatives and their use as fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1981-07-21 | — | — | US | disclosed |
| EP-0003975-B1 | DICHLOROMALEIC ACID DIAMIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BAYER AG (DE) | 1981-05-13 | — | — | EP | disclosed |
| US-4246279-A | Novel dichloromaleic acid diamide derivatives and their use as fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1981-01-20 | — | — | US | disclosed |
| EP-0003975-A1 | Dichloromaleic acid diamide derivatives, process for their preparation and their use as fungicides | BAYER AG (DE) | 1979-09-19 | — | — | EP | disclosed |