Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11325296 | 0.86 | NPSR1 (0.58) | NPSR1ALDH1A1POLBKMT2ANPC1 | |
| SCHEMBL11363030 | 0.80 | NPSR1 (0.52) | NPSR1ALDH1A1POLBKMT2ANPC1 | |
| SCHEMBL11363034 | 0.80 | NPSR1 (0.52) | NPSR1ALDH1A1POLBKMT2ANPC1 | |
| SCHEMBL9456609 | 0.80 | NPSR1 (0.64) | NPSR1ALDH1A1POLBKMT2ANPC1 | |
| SCHEMBL310005 | 0.80 | NPSR1 (0.64) | NPSR1ALDH1A1POLBKMT2ANPC1 | |
| SCHEMBL5580331 | 0.77 | POLB (0.52) | NPSR1POLBKMT2ANPC1HTT | |
| SCHEMBL1270501 | 0.76 | NPSR1 (0.58) | NPSR1ALDH1A1POLBKMT2ANPC1 | |
| SCHEMBL11562411 | 0.76 | KMT2A (0.41) | NPSR1ALDH1A1POLBKMT2ANPC1 | |
| SCHEMBL812818 | 0.74 | NPSR1 (1.00) | NPSR1ALDH1A1POLBKMT2ANPC1 | |
| SCHEMBL19778 | 0.74 | NPSR1 (0.70) | NPSR1ALDH1A1POLBKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8927579-B2 | Male contraceptive | Amobi, Nnaemkea Ikechukwu (GB) | 2015-01-06 | — | — | US | disclosed |
| US-8927579-B2 | Male contraceptive | Amobi, Nnaemkea Ikechukwu (GB) | 2015-01-06 | — | — | US | disclosed |
| US-8778968-B2 | — | — | 2014-07-15 | — | — | US | disclosed |
| US-8778968-B2 | — | — | 2014-07-15 | — | — | US | disclosed |
| EP-2081974-B1 | POLYCARBONATES AND COPOLYCARBONATES WITH IMPROVED METAL ADHESION | BAYER MATERIALSCIENCE AG (DE) | 2011-02-23 | — | — | EP | disclosed |
| US-20100029624-A1 | Male Contraceptive | KING'S COLLEGE LONDON (GB) | 2010-02-04 | — | — | US | disclosed |
| US-20100029624-A1 | Male Contraceptive | KING'S COLLEGE LONDON (GB) | 2010-02-04 | — | — | US | disclosed |
| US-7547755-B2 | (Co)polycarbonates having improved adhesion to metals | BAYER MATERIAL SCIENCE AG (DE) | 2009-06-16 | — | — | US | disclosed |
| US-7547755-B2 | (Co)polycarbonates having improved adhesion to metals | BAYER MATERIAL SCIENCE AG (DE) | 2009-06-16 | — | — | US | disclosed |
| WO-2008037364-A1 | POLYCARBONATES AND COPOLYCARBONATES WITH IMPROVED METAL ADHESION | BAYER MATERIALSCIENCE AG (DE) | 2008-04-03 | — | — | WO | disclosed |
| US-20080081896-A1 | (Co)polycarbonates having improved adhesion to metals | COVESTRO DEUTSCHLAND AG (DE) | 2008-04-03 | — | — | US | disclosed |
| US-20080081896-A1 | (Co)polycarbonates having improved adhesion to metals | COVESTRO DEUTSCHLAND AG (DE) | 2008-04-03 | — | — | US | disclosed |
| US-20050192337-A1 | Processes and polymorphs of diaryl-indolone galr3 antagonists | H. LUNDBECK A/S (DK) | 2005-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050192337-A1 | Processes and polymorphs of diaryl-indolone galr3 antagonists | GALR3, GALR1, GALR2 | NPSR1 123/4885ALDH1A1 3274/4885POLB 4358/4885 |
| US-20100029624-A1 | Male Contraceptive | NR5A1, AR, CYP19A1 | NPSR1 126/4885ALDH1A1 1598/4885POLB 2413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.