Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10391240 | 0.84 | MAPK1 (0.44) | MAPK1CRHBPCRHR2SMN1; SMN2OPRD1 | |
| SCHEMBL6092801 | 0.80 | MAPK1 (0.42) | MAPK1CRHBPCRHR2SMN1; SMN2KDM4E | |
| SCHEMBL21879900 | 0.79 | NPSR1 (0.41) | MAPK1KDM4EMAPTALDH1A1PTGES | |
| SCHEMBL3494712 | 0.75 | MAPK1 (0.55) | MAPK1SMN1; SMN2KDM4EMAPTALDH1A1 | |
| SCHEMBL3496351 | 0.75 | MAPK1 (0.55) | MAPK1SMN1; SMN2KDM4EMAPTALDH1A1 | |
| SCHEMBL10390462 | 0.72 | MAPK1 (0.75) | MAPK1CRHBPCRHR2SMN1; SMN2OPRD1 | |
| SCHEMBL24283635 | 0.72 | MAPK1 (0.55) | MAPK1MAPTALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL21298737 | 0.72 | MAPK1 (0.55) | MAPK1MAPTALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL21298717 | 0.72 | MAPK1 (0.55) | MAPK1MAPTALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL11326029 | 0.72 | OPRD1 (0.42) | MAPK1CRHBPCRHR2SMN1; SMN2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000373-B1 | IMIDAZOLE CARBOXYLIC ACIDS AND DERIVATIVES THEREOF, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PLANT GROWTH REGULANTS OR PLANT PROTECTION AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-01-07 | — | — | EP | disclosed |
| US-4182624-A | FUNGICIDES, HERBICIDES, PLANT GROWTH REGULATORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-01-08 | — | — | US | disclosed |
| EP-0000373-A1 | Imidazole carboxylic acids and derivatives thereof, process for their preparation and their use as plant growth regulants or plant protection agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-24 | — | — | EP | disclosed |