Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL667047 | 0.81 | TSHR (0.57) | TSHRALDH1A1CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL11612086 | 0.75 | TSHR (0.37) | TSHRALDH1A1 | |
| SCHEMBL11612601 | 0.73 | TSHR (0.75) | TSHRALDH1A1KDM4E | |
| SCHEMBL11609042 | 0.73 | TSHR (0.40) | TSHR | |
| SCHEMBL7849051 | 0.72 | ALDH1A1 (0.41) | TSHRALDH1A1KDM4EMAPTNOS3 | |
| SCHEMBL11614422 | 0.70 | TSHR (0.47) | TSHRALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL6136615 | 0.70 | TSHR (0.41) | TSHRKDM4E | |
| SCHEMBL6419955 | 0.70 | TSHR (0.41) | TSHRCA1CA2CA9KDM4E | |
| SCHEMBL11609024 | 0.69 | TSHR (0.36) | TSHR | |
| Hydrochloric Acid SCHEMBL11609946 | 0.69 | TSHR (0.45) | TSHRALDH1A1KDM4EMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4293542-A | PYRIDINE N-OXIDE DERIVATIVE | L'OREAL (FR) | 1981-10-06 | — | — | US | disclosed |