Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 6/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12310193 | 1.00 | ALDH1A1 (0.47) | ALDH1A1TSHRCYP3A4LMNAAPOBEC3A | |
| SCHEMBL10081659 | 0.98 | ALDH1A1 (0.48) | ALDH1A1TSHRCYP3A4LMNAAPOBEC3A | |
| SCHEMBL7760169 | 0.94 | ALDH1A1 (0.48) | ALDH1A1TSHRCYP3A4LMNAAPOBEC3A | |
| SCHEMBL34470452 | 0.91 | ALDH1A1 (0.45) | ALDH1A1TSHRCYP3A4LMNAAPOBEC3A | |
| SCHEMBL32682135 | 0.91 | ALDH1A1 (0.45) | ALDH1A1TSHRCYP3A4LMNAAPOBEC3A | |
| SCHEMBL32682136 | 0.91 | ALDH1A1 (0.45) | ALDH1A1TSHRCYP3A4LMNAAPOBEC3A | |
| Ethylene Glycol SCHEMBL18940268 | 0.87 | ALDH1A1 (0.45) | ALDH1A1TSHRCYP3A4LMNAAPOBEC3A | |
| SCHEMBL141388 | 0.86 | ALDH1A1 (0.56) | ALDH1A1TSHRCYP3A4LMNASMN1; SMN2 | |
| SCHEMBL562668 | 0.84 | ALDH1A1 (0.54) | ALDH1A1TSHRCYP3A4LMNASMN1; SMN2 | |
| SCHEMBL31756060 | 0.84 | ALDH1A1 (0.54) | ALDH1A1TSHRCYP3A4LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4281093-A | Catalyst compositions and their use in the preparation of release coatings | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-07-28 | — | — | US | disclosed |
| EP-0015346-A1 | Catalyst compositions and their use in the preparation of release coatings | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-09-17 | — | — | EP | disclosed |