Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2549420 | 0.97 | CA12 (0.40) | CA12CA1CA9TSHRLMNA | |
| SCHEMBL27032875 | 0.88 | DNM1 (0.48) | CA12CA1CA9TSHRLMNA | |
| SCHEMBL15606108 | 0.84 | CA12 (0.33) | CA12CA1CA9CA2 | |
| SCHEMBL15606105 | 0.78 | DNM1 (0.35) | CA12CA1CA9DNM1 | |
| Biphenyl SCHEMBL11313974 | 0.77 | GAA (0.47) | TSHR | |
| SCHEMBL10459535 | 0.76 | CA12 (0.35) | CA12CA1CA9CA2 | |
| SCHEMBL15606112 | 0.75 | DNM1 (0.32) | CA12CA1CA9DNM1 | |
| SCHEMBL16405983 | 0.73 | CA12 (0.37) | CA12CA1CA9TSHRLMNA | |
| SCHEMBL16582983 | 0.73 | CA12 (0.37) | CA12CA1CA9TSHRLMNA | |
| SCHEMBL17691275 | 0.73 | CA12 (0.37) | CA12CA1CA9TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4302571-A | TERMINATED AT BOTH ENDS WITH SILANOIC HYDROXY GROUPS AND AN ORGANOSILANE OR ORGANOPOLYSILOXANE WITH HYDROLYZABLE GROUPS TO SERVE AS CROSSLINKING AGENTS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1981-11-24 | — | — | US | disclosed |