Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22588787 | 0.98 | ACHE (0.59) | ACHEEPHX2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL11338749 | 0.92 | ACHE (0.75) | ACHEEPHX2 | |
| SCHEMBL11325978 | 0.91 | ACHE (0.68) | ACHEEPHX2 | |
| SCHEMBL13331638 | 0.88 | ACHE (0.58) | ACHEEPHX2 | |
| SCHEMBL11325901 | 0.87 | ACHE (0.57) | ACHEEPHX2 | |
| SCHEMBL11339356 | 0.87 | ACHE (0.51) | ACHEEPHX2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL10817081 | 0.86 | ACHE (0.81) | ACHEEPHX2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL22588838 | 0.85 | ACHE (0.64) | ACHEEPHX2 | |
| SCHEMBL28289954 | 0.85 | ACHE (0.49) | ACHEEPHX2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9927890 | 0.84 | EPHX2 (0.74) | ACHEEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260552-A | INSECTICIDES, HERBICIDES | UNIROYAL, INC. (US) | 1981-04-07 | — | — | US | disclosed |
| US-4160846-A | Method for controlling insects with tetrasubstituted organotin compounds | UNIROYAL, INC. (US) | 1979-07-10 | — | — | US | disclosed |