Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11338249 | 0.87 | ALDH1A1 (0.42) | ALDH1A1CYP2C9CYP3A4CYP2C19MEN1 | |
| SCHEMBL10179848 | 0.79 | MEN1 (0.43) | ALDH1A1CYP2C9MEN1KMT2ATSHR | |
| SCHEMBL8834905 | 0.79 | ALDH1A1 (0.65) | ALDH1A1CYP2C9CYP3A4CYP2C19MEN1 | |
| SCHEMBL8834639 | 0.79 | ALDH1A1 (0.65) | ALDH1A1CYP2C9CYP3A4CYP2C19MEN1 | |
| SCHEMBL8834888 | 0.79 | ALDH1A1 (0.65) | ALDH1A1CYP2C9CYP3A4CYP2C19MEN1 | |
| SCHEMBL8835388 | 0.79 | ALDH1A1 (0.65) | ALDH1A1CYP2C9CYP3A4CYP2C19MEN1 | |
| SCHEMBL9299392 | 0.79 | ALDH1A1 (0.65) | ALDH1A1CYP2C9CYP3A4CYP2C19MEN1 | |
| SCHEMBL8834611 | 0.79 | ALDH1A1 (0.65) | ALDH1A1CYP2C9CYP3A4CYP2C19MEN1 | |
| SCHEMBL9299607 | 0.79 | ALDH1A1 (0.65) | ALDH1A1CYP2C9CYP3A4CYP2C19MEN1 | |
| SCHEMBL8834960 | 0.79 | ALDH1A1 (0.65) | ALDH1A1CYP2C9CYP3A4CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260552-A | INSECTICIDES, HERBICIDES | UNIROYAL, INC. (US) | 1981-04-07 | — | — | US | disclosed |
| US-4160846-A | Method for controlling insects with tetrasubstituted organotin compounds | UNIROYAL, INC. (US) | 1979-07-10 | — | — | US | disclosed |