SCHEMBL113262

SCHEMBL113262

Cc1cc(Cl)c(OCC(=O)O)c(Cl)c1

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.61
KDM4E B2RXH2 4/20 0.54
PKM P14618 1/20 0.54
HTT P42858 1/20 0.54
MCL1 Q07820 1/20 0.53
HIF1A Q16665 1/20 0.49
ALDH1A1 P00352 1/20 0.49
TDP1 Q9NUW8 2/20 0.47
TSHR P16473 1/20 0.46
CYP2C19 P33261 1/20 0.45
PTGDR2 Q9Y5Y4 1/20 0.44
HPGD P15428 1/20 0.44
ELANE P08246 1/20 0.44
CD69 Q07108 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL481443 0.84 KMT2A (0.66) KMT2AKDM4EPKMHTTMCL1
Hydrochloric Acid SCHEMBL10388885 0.82 KMT2A (0.63) KMT2AKDM4EPKMHTTMCL1
SCHEMBL5211055 0.81 KMT2A (0.58) KMT2AKDM4EPKMHTTMCL1
SCHEMBL11576418 0.81 PLAU (0.64) KMT2AKDM4EPKMHTTMCL1
SCHEMBL5533461 0.81 KMT2A (0.61) KMT2AKDM4EPKMHTTMCL1
SCHEMBL6746937 0.81 THRB (0.54) KMT2AKDM4EPKMMCL1ALDH1A1
SCHEMBL1890174 0.80 KDM4E (0.57) KMT2AKDM4EPKMHTTMCL1
SCHEMBL5834958 0.80 CYP2C19 (0.56) KMT2AKDM4EPKMHTTMCL1
SCHEMBL13996135 0.80 GAA (0.49) KMT2AKDM4EPKMALDH1A1TDP1
SCHEMBL2059355 0.80 CSNK2A2 (0.49) KMT2AKDM4EMCL1ALDH1A1PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4593 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035402-A1 C10-ALKYLENE SUBSTITUTED 13-MEMBERED MACROLIDES AND USES THEREOF ZIKANI THERAPEUTICS INC (US) 2026-02-05 US claimed
EP-3947382-B1 COMPOUNDS FOR USES IN PHARMACOLOGICAL INDUCTION OF HBF FOR TREATMENT OF SICKLE CELL DISEASE AND BETA-THALASSEMIA ACADEMIA SINICA (TW) 2025-09-24 EP claimed
US-12060334-B2 3-substituted phenazine derivatives as antimicrobial agents UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-08-13 US claimed
EP-2991655-B1 COMPOSITIONS AND METHODS FOR ALTERING SECOND MESSENGER SIGNALING MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2024-04-10 EP claimed
EP-3606528-B1 TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF BROAD INST INC (US) 2023-10-18 EP claimed
US-11634449-B2 Macrolides and methods of their preparation and use PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-04-25 US claimed
EP-3649135-B1 SYNTHESIS OF HALICHONDRINS HARVARD COLLEGE (US) 2022-12-28 EP claimed
US-20220332747-A1 MACROLIDES AND METHODS OF THEIR PREPARATION AND USE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2022-10-20 US claimed
EP-3291676-B1 MITRAGYNINE ANALOGS AND USES THEREOF MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2022-08-17 EP claimed
US-11241435-B2 Uses of salt-inducible kinase (SIK) inhibitors for treating osteoporosis THE GENERAL HOSPITAL CORPORATION (US) 2022-02-08 US claimed
US-20100048957-A1 METHOD TO PREPARE PURE CURCUMIN KIM DARRICK S H L 2010-02-25 US claimed
EP-2037762-A4 METHOD TO PREPARE PURE CURCUMIN KIM DARRICK S H L (US) 2009-07-08 EP claimed
EP-2037762-A1 METHOD TO PREPARE PURE CURCUMIN Kim, Darrick S.H.L. (US) 2009-03-25 EP claimed
WO-2007143635-A1 METHOD TO PREPARE PURE CURCUMIN KIM DARRICK S (US) 2007-12-13 WO claimed
EP-0781293-A4 COMPOSITIONS FOR ENZYME CATALYZED TEMPLATE-INDEPENDENT CREATION OF PHOSPHODIESTER BONDS USING PROTECTED NUCLEOTIDES HIATT ANDREW C ROSE HIATT BIOT (US) 1999-05-26 EP claimed
US-5808045-A Compositions for enzyme catalyzed template-independent creation of phosphodiester bonds using protected nucleotides Hiatt, Andrew C. (US) 1998-09-15 US claimed
EP-0781293-A1 COMPOSITIONS FOR ENZYME CATALYZED TEMPLATE-INDEPENDENT CREATION OF PHOSPHODIESTER BONDS USING PROTECTED NUCLEOTIDES Hiatt, Andrew C. (US) 1997-07-02 EP claimed
WO-1996007669-A1 COMPOSITIONS FOR ENZYME CATALYZED TEMPLATE-INDEPENDENT CREATION OF PHOSPHODIESTER BONDS USING PROTECTED NUCLEOTIDES ROSE-HIATT BIOTECHNOLOGY PARTNERSHIP (US) 1996-03-14 WO claimed
US-5478928-A Useful as antiviral agents in the treatment and prevention of AIDS SOUTHERN RESEARCH INSTITUTE (US) 1995-12-26 US claimed
WO-1995011685-A1 2',3'-DIDEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AGENTS SOUTHERN RESEARCH INSTITUTE (US) 1995-05-04 WO claimed